CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis
Y Jiang, J Zhao, R Li, Y Liu, L Zhou, C Wang… - Journal of Experimental …, 2022 - Springer
Background Ferroptosis is a novel form of iron-dependent cell death and participates in the
malignant progression of glioblastoma (GBM). Although circular RNAs (circRNAs) are found …
malignant progression of glioblastoma (GBM). Although circular RNAs (circRNAs) are found …
Epigenetic alterations in glioblastomas: Diagnostic, prognostic and therapeutic relevance
L Montella, M Cuomo, N Del Gaudio… - … Journal of Cancer, 2023 - Wiley Online Library
Glioblastoma, the most common and heterogeneous tumor affecting brain parenchyma, is
dismally characterized by a very poor prognosis. Thus, the search of new, more effective …
dismally characterized by a very poor prognosis. Thus, the search of new, more effective …
Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma
X Geng, Y Zhang, X Lin, Z Zeng, J Hu, L Hao, J Xu… - Cell Death & …, 2022 - nature.com
Exosome-mediated delivery of circular RNAs (circRNAs) is implicated in cancer progression.
However, the role of exosomal circRNAs in the chemotherapy resistance of tumours remains …
However, the role of exosomal circRNAs in the chemotherapy resistance of tumours remains …
New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs
Background Glioblastoma (GBM) is the most frequent type of primary brain cancer, having a
median survival of only 15 months. The current standard of care includes a combination of …
median survival of only 15 months. The current standard of care includes a combination of …
GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin
H Wang, D Wang, Y Shen, C Sun, Q Hu, L Jiang… - Cancer gene …, 2023 - nature.com
It has been widely reported that glioma stem-like cells (GSCs) serve a crucial role in the
malignant progression of glioma. In particular, recent studies have reported that long non …
malignant progression of glioma. In particular, recent studies have reported that long non …
Protein structuromics: A new method for protein structure–function crosstalk in glioma
N Xiao, W Yang, J Wang, J Li, R Zhao… - Proteins: Structure …, 2024 - Wiley Online Library
Glioma is a type of tumor that starts in the glial cells of the brain or spine. Since the 1800s,
when the disease was first named, its survival rates have always been unsatisfactory …
when the disease was first named, its survival rates have always been unsatisfactory …
CircKPNB1 mediates a positive feedback loop and promotes the malignant phenotypes of GSCs via TNF-α/NF-κB signaling
Y Jiang, J Zhao, Y Liu, J Hu, L Gao, H Wang… - Cell Death & …, 2022 - nature.com
Glioma stem cells (GSCs) are a special kind of cells in GBM showing tumor initiation, self-
renewal, and multi-lineage differentiation abilities. Finding novel circRNAs related to GSCs …
renewal, and multi-lineage differentiation abilities. Finding novel circRNAs related to GSCs …
Hypoxia-Inducible Factor-Dependent and Independent Mechanisms Underlying Chemoresistance of Hypoxic Cancer Cells
PWT Lee, LR Koseki, T Haitani, H Harada… - Cancers, 2024 - mdpi.com
Simple Summary In solid tumors, oxygen concentration varies between different regions.
Generally, while oxygen supply is sufficient in the vicinity of blood vessels, the concentration …
Generally, while oxygen supply is sufficient in the vicinity of blood vessels, the concentration …
[HTML][HTML] The landscape of circRNAs in gliomas temozolomide resistance: Insights into molecular pathways
A Mafi, N Hedayati, S Kahkesh, S Khoshayand… - Non-coding RNA …, 2024 - Elsevier
As the deadliest type of primary brain tumor, gliomas represent a significant worldwide
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …
Diterpenoid honatisine overcomes temozolomide resistance in glioblastoma by inducing mitonuclear protein imbalance through disruption of TFAM-mediated mtDNA …
Z Li, K Sai, G Ma, F Chen, X Xu, L Chen, S Wang, W Li… - Phytomedicine, 2024 - Elsevier
Background Glioblastoma (GBM) represents as the most formidable intracranial malignancy.
The systematic exploration of natural compounds for their potential applications in GBM …
The systematic exploration of natural compounds for their potential applications in GBM …