Blood–brain barrier disruption and perivascular spaces in small vessel disease and neurodegenerative diseases: a review on MRI methods and insights
PHM Voorter, M van Dinther, WJ Jansen… - Journal of Magnetic …, 2024 - Wiley Online Library
Perivascular spaces (PVS) and blood–brain barrier (BBB) disruption are two key features of
cerebral small vessel disease (cSVD) and neurodegenerative diseases that have been …
cerebral small vessel disease (cSVD) and neurodegenerative diseases that have been …
Diffusion tensor image analysis ALong the perivascular space (DTI-ALPS): revisiting the meaning and significance of the method
The ALPS-index was found to be an indicator of a number of conditions related to the
glymphatic system. Thus, although this was expected in the original report, the results of the …
glymphatic system. Thus, although this was expected in the original report, the results of the …
Perivascular spaces, diffusivity along perivascular spaces, and free water in cerebral small vessel disease
Background and Objectives Previous studies have linked the MRI measures of perivascular
spaces (PVSs), diffusivity along the perivascular spaces (DTI-ALPS), and free water (FW) to …
spaces (PVSs), diffusivity along the perivascular spaces (DTI-ALPS), and free water (FW) to …
[HTML][HTML] The relationship between inflammation, impaired glymphatic system, and neurodegenerative disorders: A vicious cycle
The term “glymphatic” emerged roughly a decade ago, marking a pivotal point in
neuroscience research. The glymphatic system, a glial-dependent perivascular network …
neuroscience research. The glymphatic system, a glial-dependent perivascular network …
[HTML][HTML] The relationship between amyloid pathology, cerebral small vessel disease, glymphatic dysfunction, and cognition: a study based on Alzheimer's disease …
Background Glymphatic dysfunction is a crucial pathway for dementia. Alzheimer's disease
(AD) pathologies co-existing with cerebral small vessel disease (CSVD) is the most common …
(AD) pathologies co-existing with cerebral small vessel disease (CSVD) is the most common …
[HTML][HTML] Pathophysiology of cerebral small vessel disease: a journey through recent discoveries
Cerebral small vessel disease (cSVD) encompasses a heterogeneous group of age-related
small vessel pathologies that affect multiple regions. Disease manifestations range from …
small vessel pathologies that affect multiple regions. Disease manifestations range from …
Association of optic disc pallor and RNFL thickness with cerebral small vessel disease in the PREVENT‐Dementia study
INTRODUCTION We tested associations between two retinal measures (optic disc pallor,
peripapillary retinal nerve fiber layer [pRNFL] thickness) and four magnetic resonance …
peripapillary retinal nerve fiber layer [pRNFL] thickness) and four magnetic resonance …
Impaired cerebral interstitial fluid dynamics in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leucoencephalopathy, caused by cysteine-altering variants in NOTCH3, is the most …
leucoencephalopathy, caused by cysteine-altering variants in NOTCH3, is the most …
Clinical magnetic resonance imaging evaluation of glymphatic function
The glymphatic system is a system of specialized perivascular spaces in the brain that
facilitates removal of toxic waste solutes from the brain. Evaluation of glymphatic system …
facilitates removal of toxic waste solutes from the brain. Evaluation of glymphatic system …
Motor progression phenotypes in early-stage Parkinson's Disease: a clinical prediction model and the role of glymphatic system imaging biomarkers
P He, Y Gao, L Shi, Y Li, S Jiang, Z Tie, Y Qiu, G Ma… - Neuroscience …, 2023 - Elsevier
Background Substantial heterogeneity of motor symptoms in Parkinson's disease (PD)
poses a challenge to disease prediction. Objectives The aim of this study was to construct a …
poses a challenge to disease prediction. Objectives The aim of this study was to construct a …