Maintaining organ viability after donation until transplantation is critically important for
optimal graft function and survival. To date, static cold storage is the most widely used form …

Solid organ transplantation was one of the greatest medical advances during the past few
decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic …

With the successful testing of the immunosuppressive effects of cyclosporine in transplant
patients in 1978, the field of organ transplants began an exponential growth. With that, the …

In addition to immunological and wound healing cell and platelet delivery, ion stasis and
nutrient supply, blood delivers oxygen to cells and tissues and removes metabolic wastes …

Acute renal failure is a serious consequence of renal ischemia. The diagnosis carries an
associated high mortality rate. When blood flow to the kidneys is inadequate to supply …

Moving rapidly from science fiction to science fact, cryopreservation is an integral part of
many research, development, and production processes in industry and academia. The …

Improved preservation techniques have the potential to improve transplant outcomes by
better maintaining donor organ quality and by making more organs available for …

The depletion of biochemical energy stores during anoxic ischemic preservation is a major
problem affecting the viability of the graft in transplantation medicine. After cessation of …

Since the advent of University of Wisconsin preservation solution in the 1980s clinicians
have learned to work within its confines. While affording improved outcomes, considerable …

OBJECTIVES: Especially for preservation of marginal donor organs, machine perfusion (MP)
and retrograde oxygen persufflation (ROP) are alternatives to cold storage (CS). Using a …