Despite rapid advances in modern medical technology and significant improvements in
survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal …

Cancer is one of the major diseases that cause a high number of deaths globally. Of the
major types of cancers, lung cancer is known to be the most chronic form of cancer in the …

Utilization of tobacco products is a global epidemic that causes a health threat among the
adolescents and adults of the world. If the current pattern perpetuates, it is estimated to …

Breast cancer (BC) is one of the most common causes of cancer in the world and the second
leading cause of cancer deaths among women. Mortality is associated mainly with the …

Introduction Lung cancer (LC) remains a disease with poor prognosis despite recent
advances in treatments. Here, we aimed at summarizing the current scientific evidence on …

Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Cancer is driven by genomic mutations in 'cancer driver'genes, which have essential roles in
tumor development. These mutations may be caused by exposure to mutagens in the …

This Opinion article discusses emerging evidence of direct contributions of nicotine to
cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding …

Post-translational modifications (PTMs) play key roles in regulating cell signaling and
physiology in both normal and cancer cells. Advances in mass spectrometry enable high …

Acetylcholine (ACh) is best known as a neurotransmitter and was the first such molecule
identified. ACh signalling in the neuronal cholinergic system has long been known to …