Antibodies can completely suppress or enhance the antibody response to their specific
antigen by several hundredfold. Immunoglobulin M (IgM) enhances antibody responses via …

Antibodies administered in vivo together with the antigen they are specific for can regulate
the immune response to that antigen. This phenomenon is called antibody‐mediated …

Ag retention on follicular dendritic cells (FDCs) is essential for B cell activation and clonal
selection within germinal centers. Protein Ag is deposited on FDCs after formation of …

Publisher Summary This chapter describes the interaction of immune complexes (ICs) with
complement and with the cells of the immune system. The effect of immune complexes …

The discovery that the thymus was involved in the development of the immune system
(Miller, 1961; Archer et al, 1962; Jankovic et al, 1962) ushered in the “golden age of …

The ability of IgM antibodies to specifically enhance the thymus-dependent humoral immune
response to particulate antigens is well documented. We have used two approaches to test …

Publisher Summary This chapter discusses lymphocyte receptors for immunoglobulin (Ig).
The methods used to detect lymphocyte receptors for Ig vary widely both as the type of …

Anti-D is routinely and effectively used to prevent hemolytic disease of the fetus and
newborn (HDFN) caused by the antibody response to the D antigen on fetal RBCs. Anti-D is …

The binding of covalently cross-linked oligomers of rabbit IgG antibodies to tumor cells
resembling macrophages and lymphocytes and to normal spleen cells has been measured …

Abstract Isologous IgG2a, and IgG2b anti‐hapten antibodies injected along with
trinitrophenylated or fluoresceinated keyhole limpet hemocyanin (KLH) were found to …