Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …

While sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) is due to
arrhythmias, the guidelines for prediction of SCD are based solely on non …

Background—Brugada syndrome (BrS) is associated with lethal arrhythmias, which are
linked to specific ST-segment changes (type-1 BrS-ECG) and the right ventricle (RV). The …

Aims Paced electrogram fractionation analysis (PEFA) has been assessed for the prediction
of sudden cardiac death (SCD) in a large-scale, prospective study of patients with …

Aims A novel electrophysiological technique, paced electrogram fractionation analysis
(PEFA), which measures activation delay of stimulated beats through the myocardium, has …

Ventricular arrhythmogenesis in long QT 3 syndrome (LQT3) involves both triggered activity
and re‐entrant excitation arising from delayed ventricular repolarization. Effects of specific L …

Brugada syndrome (BrS) is associated with a loss of Na+ channel function and an increased
incidence of rapid polymorphic ventricular tachycardia (VT) and sudden cardiac death. A …

We explored for relationships between SCN5A haploinsufficiency, implicated in clinical
arrhythmogenicity, and right ventricular (RV) conduction disorders in Langendorff-perfused …

The clinical effects of hypokalemia including action potential prolongation and
arrhythmogenicity suppressible by lidocaine were reproduced in hypokalemic (3.0 mM K+) …

Whilst the decision regarding defibrillator implantation in a patient with a familial sudden
cardiac death syndrome is likely to be most significant for any particular individual, the …