Annexin A5 (AnxA5) binds to phospholipid bilayers, forming two-dimensional crystals that
block the phospholipids from availability for coagulation enzyme reactions. Antiphospholipid …

This review provides a critical and thorough overview of the radiopharmaceutical
development and in vivo evaluation of all apoptosis-detecting radioligands that have …

It is 20 years since the use of a radioimmunoassay enabled an association to be described
between antibodies to the anionic phospholipid cardiolipin and a set of clinical features [1] …

The phospholipid binding protein, annexin A5 (AnxA5), has potent anticoagulant properties
that result from its forming 2-dimensional crystals over phospholipids, blocking the …

OBJECTIVE: We investigated whether levels of annexin A5, evidence for resistance to
annexin A5 activity, and levels anti–annexin A5 antibodies might be altered in women with a …

Whereas antiphospholipid antibodies (aPL) are associated with thrombotic events and
recurrent spontaneous abortion (RSA), the contribution of anti-β2 glycoprotein 1 (β2GP1) …

Problem Antiphospholipid syndrome (APS) may affect placental functions through several
possible mechanisms. Interaction of antiphospholipid antibodies (aPL) with cells involved in …

OBJECTIVE: The present study was aimed at a comprehensive analysis of acquired
thrombophilia in a large series of Indian women with fetal loss. STUDY DESIGN: Four …

Anti-phospholipid antibodies (APA) are heterogeneous group of autoantibodies that target
phospholipid or phospholipid-binding proteins. APAs were previously shown to induce …

Targeting of the annexin A5 anticoagulant shield may be a significant mechanism for
thrombosis and pregnancy losses in APS. This may occur via high affinity antibodies that …