Cystic fibrosis (CF) airway epithelia express a defect in adenosine 3', 5'-cyclic
monophosphate (cAMP)-dependent regulation of apical membrane Cl-channels. Recent …

Control of airway function during and after exercise in asthmatics. Med. Sci. Sports Exerc.,
Vol. 31, No. 1 (Suppl.), pp. S4-S11, 1999. In asthmatics, airway function can be quite …

Abnormal mucociliary transport is improvement by the action of theophylline, and this effect
can be attributed to several mechanisms. The drug may directly and indirectly mediate the …

Even though the same Cl channel (CFTR) is common to certain fluid transport functions that
are oppositely directed, ie, secretion and absorption, only fluid secretion has clearly been …

Increase of Ca 2+ influx in Cystic Fibrosis (CF) cells has been reported to be related to
Transient Receptor Potential Canonical (TRPC6) channel, which is implicated in a functional …

In many species submucosal glands are an important source of tracheal mucus, but the
extent to which mucociliary clearance (MCC) depends on gland secretion is unknown. To …

Ion channels, such as the epithelial sodium channel (ENaC), are essential for maintaining a
fluid-free middle ear cavity by controlling periciliary fluid. Deviations from the normal volume …

Nasal mucociliary clearance was measured with two methods in 8 patients with Sjøgren's
syndrome and in 6 normal subjects. The movement of two different tracers placed 1.5 cm …

1. The whole trachea of the ferret has been isolated in vitro in an organ bath and used to
study the transport of bovine serum albumin (BSA) and two dextrans (70,000 and 9000 Da) …

We studied the Cl-permeability properties of apical and basolateral membranes of human
reabsorptive sweat duct (RSD) from normal and cystic fibrosis (CF) subjects. In normal ducts …