Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal
monogenic disorder. It has large inter-and intra-familial variability explained to a large extent …

Autosomal dominant polycystic kidney disease is a genetic disorder associated with
substantial variability in its natural course within and between affected families …

A major hallmark of chronic kidney injury is fibrosis, which is characterized by increased
accumulation of extracellular matrix components that replace the damaged tissue. Normally …

Polycystic kidney disease (PKD) is a commonly inherited disorder characterized by cyst
formation and fibrosis (Wilson, N Engl J Med 350: 151–164, 2004) and is caused by …

The age on onset of decline in renal function and end-stage renal disease (ESRD) in
autosomal polycystic kidney disease (ADPKD) is highly variable and there are currently no …

In autosomal dominant polycystic kidney disease (ADPKD), the inexorable growth of
numerous fluid-filled cysts leads to massively enlarged kidneys, renal interstitial damage …

Objective. Renal ischemia/reperfusion injury (RI/RI) is the main cause of acute kidney injury.
Total glucosides of paeony (TGP) are a traditional Chinese medicine. This study was aimed …

Polycystic kidney disease (PKD) is a common genetic disorder characterized by formations
of numerous cysts in kidneys and most caused by PKD1 or PKD2 mutations in autosomal …

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by innumerous
fluid-filled cysts and progressive deterioration of renal function. Previously, we showed that …

Purpose In this placebo-controlled trial, we aimed to evaluate the clinical results of using
PDE-5 inhibitor, tadalafil 5 mg OD, for management of CP/CPPS. Patients and methods 140 …