Vaccination is generally considered to be the most effective method of preventing infectious
diseases. All vaccinations work by presenting a foreign antigen to the immune system in …

In this paper, current prediction methods and algorithms for both T‐and B cell epitopes are
reviewed, and a comprehensive summary of epitope prediction software and databases …

The development of immunological therapies that incorporate peptide antigens presented to
T cells by MHC proteins is a long sought-after goal, particularly for cancer, where mutated …

Peptides that bind to major histocompatibility complex products (MHC) are known to exhibit
certain sequence motifs which, though common, are neither necessary nor sufficient for …

A simple and fast free energy scoring function (Fresno) has been developed to predict the
binding free energy of peptides to class I major histocompatibility (MHC) proteins. It differs …

Understanding the mechanisms involved in the activation of an immune response is
essential to many fields in human health, including vaccine development and personalized …

A set of 102 peptides with affinity for the class I MHC HLA-A* 0201 molecule was subjected
to three-dimensional quantitative structure− affinity relationship (3D QSAR) studies using …

T-cell recognition of peptide/major histocompatibility complex (MHC) is a prerequisite for
cellular immunity. Recently, there has been an influx of bioinformatics tools to facilitate the …

The class I major histocompatibility complex (MHC) is capable of binding peptides derived
from intracellular proteins and displaying them at the cell surface. The recognition of these …

JenPep is a relational database containing a compendium of thermodynamic binding data
for the interaction of peptides with a range of important immunological molecules: the major …