The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity
of cancer phenotypes and genotypes into a provisional set of underlying principles. As …

Bulk sequencing methodologies have allowed us to make great progress in cancer
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …

We determined the relationships between DNA sequence variation and DNA methylation
using blood samples from 3,799 Europeans and 3,195 South Asians. We identify …

Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena,
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …

Cancer is a public health problem of great concern, and it is also one of the main causes of
death in the world. Cancer is a disease characterized by dysregulation of diverse cellular …

Background: Tumorigenesis is associated with deregulation of nutritional requirements,
intermediary metabolites production, and microenvironment interactions. Unlike their normal …

Nimbolide, a major limonoid constituent of Azadirachta indica, commonly known as neem,
has attracted increasing research attention owing to its wide spectrum of pharmacological …

Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

Pancreatic cancer (PACA), which is characterized by an immunosuppressive nature,
remains one of the deadliest malignancies worldwide. Aberrant DNA methylation (DNAm) …

Phytochemicals are natural compounds found in food ingredients with a variety of health-
promoting properties. Phytochemicals improve host health through their direct systematic …