Diet as a whole, encompassing food composition, calorie intake, and the length and
frequency of fasting periods, affects the time span in which health and functional capacity …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

There is emerging evidence that diet has a major modulatory influence on brain-gut-
microbiome (BGM) interactions with important implications for brain health, and for several …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected,
debilitating multi-systemic disease without diagnostic marker or therapy. Despite evidence …

The global human population has recently experienced an increase in life expectancy with a
mounting concern about the steady rise in the incidence of age-associated chronic diseases …

Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

In recent decades, traditional eating habits have been replaced by a more globalized diet,
rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary …

Alzheimer's disease (AD) is the most common form of senile dementia, accounting for up to
70% of dementia cases. AD is a slowly progressive disease, which causes global mental …

Declining health, gut dysbiosis, and cognitive impairments are hallmarks of advanced age.
While caloric restriction is known to robustly extend the healthspan and alter gut microbiome …