Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
M Cornaglia, T Lehnert, MAM Gijs - Lab on a Chip, 2017 - pubs.rsc.org
In a typical high-throughput drug screening (HTS) process, up to millions of chemical
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …
Studying Parkinson's disease using Caenorhabditis elegans models in microfluidic devices
Parkinson's disease (PD) is a progressive neurological disorder associated with the loss of
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …
Cell counting and velocity algorithms for hydrodynamic study of unsteady biological flows in micro-channels
In this paper, the combination of two algorithms, a cell counting algorithm and a velocity
algorithm based on a Digital Particle Image Velocimetry (DPIV) method, is presented to …
algorithm based on a Digital Particle Image Velocimetry (DPIV) method, is presented to …
A review of biosensing techniques for detection of trace carcinogen contamination in food products
Carcinogen contaminations in the food chain, for example heavy metal ions, pesticides,
acrylamide, and mycotoxins, have caused serious health problems. A major objective of …
acrylamide, and mycotoxins, have caused serious health problems. A major objective of …
An integrated platform enabling optogenetic illumination of Caenorhabditis elegans neurons and muscular force measurement in microstructured environments
Optogenetics has been recently applied to manipulate the neural circuits of Caenorhabditis
elegans (C. elegans) to investigate its mechanosensation and locomotive behavior, which is …
elegans (C. elegans) to investigate its mechanosensation and locomotive behavior, which is …
High-throughput light sheet imaging of adult and larval C. elegans Parkinson's disease model using a low-cost optofluidic device and a fluorescent microscope
F Rahimpouresfahani, N Tabatabaei, P Rezai - RSC advances, 2024 - pubs.rsc.org
Recent advancements at the interface of microfluidics technology and light sheet
fluorescence microscopy have opened the door for high-throughput and high-content …
fluorescence microscopy have opened the door for high-throughput and high-content …
Recent Advances and Trends in Microfluidic Platforms for C. elegans Biological Assays
F Kamili, H Lu - Annual Review of Analytical Chemistry, 2018 - annualreviews.org
Microfluidics has proven to be a key tool in quantitative biological research. The C. elegans
research community in particular has developed a variety of microfluidic platforms to …
research community in particular has developed a variety of microfluidic platforms to …
Microfluidic device for analysis of gas-evoked neuronal sensing in C. elegans
It is a challenging task to realize gaseous stimulations on Caenorhabibditis elegans for in
vivo neuronal analysis of chemo-sensing, due to the difficulties in gas control and worm …
vivo neuronal analysis of chemo-sensing, due to the difficulties in gas control and worm …
Immobilization of live Caenorhabditis elegans individuals using an ultra-thin polydimethylsiloxane microfluidic chip with water retention
M Suzuki, T Sakashita, T Funayama - JoVE (Journal of Visualized …, 2019 - jove.com
Radiation is widely used for biological applications and for ion-beam breeding, and among
these methods, microbeam irradiation represents a powerful means of identifying …
these methods, microbeam irradiation represents a powerful means of identifying …
Comparative toxicity of lead (Pb2+), copper (Cu2+), and mixtures of lead and copper to zebrafish embryos on a microfluidic chip
Y Li, X Yang, Z Chen, B Zhang, J Pan, X Li, F Yang… - …, 2015 - pubs.aip.org
Investigations were conducted to determine acute effects of Pb 2+ and Cu 2+ presented
individually and collectively on zebrafish embryos. Aquatic safety testing requires a cheap …
individually and collectively on zebrafish embryos. Aquatic safety testing requires a cheap …