Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 3 …

SH Kennedy, RW Lam, RS McIntyre… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Results of the European Group for the Study of Resistant Depression (GSRD)—basis for further research and clinical practice

L Bartova, M Dold, A Kautzky, C Fabbri… - The World Journal of …, 2019 - Taylor & Francis
Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines

A Cleare, CM Pariante, AH Young… - Journal of …, 2015 - journals.sagepub.com
A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Evidence-based pharmacotherapy of treatment-resistant unipolar depression

M Dold, S Kasper - International journal of psychiatry in clinical …, 2017 - Taylor & Francis
Abstract Treatment resistance to the antidepressive pharmacotherapy represents one of the
most important clinical challenges in the pharmacological management of unipolar …

Pharmacological interventions for treatment‐resistant depression in adults

P Davies, S Ijaz, D Kessler, G Lewis… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Although antidepressants are often a first‐line treatment for adults with
moderate to severe depression, many people do not respond adequately to medication, and …

[HTML][HTML] Chronic and treatment resistant depression: diagnosis and stepwise therapy

T Bschor, M Bauer, M Adli - Deutsches Ärzteblatt International, 2014 - ncbi.nlm.nih.gov
Chronic and Treatment Resistant Depression - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

Switching the antidepressant after nonresponse in adults with major depression: a systematic literature search and meta-analysis

T Bschor, H Kern, J Henssler… - The Journal of Clinical …, 2016 - psychiatrist.com
Objective: Nonresponders to antidepressant monotherapy during acute treatment of major
depression are often switched to a new antidepressant. The objective of this meta-analysis …

[HTML][HTML] Optimising first-and second-line treatment strategies for untreated major depressive disorder—the SUN☺ D study: a pragmatic, multi-centre, assessor-blinded …

T Kato, TA Furukawa, A Mantani, K Kurata, H Kubouchi… - BMC medicine, 2018 - Springer
Background For patients starting treatment for depression, current guidelines recommend
titrating the antidepressant dosage to the maximum of the licenced range if tolerated. When …

[HTML][HTML] Early switching strategies in antidepressant non-responders: current evidence and future research directions

PA Kudlow, RS McIntyre, RW Lam - CNS drugs, 2014 - Springer
Studies have found that up to two-thirds of patients with major depressive disorder (MDD) do
not fully respond to the first antidepressant. While switching antidepressants is a common …

Are antidepressants effective? A debate on their efficacy for the treatment of major depression in adults

T Bschor, LL Kilarski - Expert review of neurotherapeutics, 2016 - Taylor & Francis
Recently, the efficacy of antidepressants, a treatment used by 11% of US American adults,
has been debated. Thousands of randomized controlled trials (RCTs) have been used to …