Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Colorectal cancer statistics, 2023

RL Siegel, NS Wagle, A Cercek… - CA: a cancer journal …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC statistics …

Metabolism and colorectal cancer

JC Sedlak, ÖH Yilmaz, J Roper - Annual Review of Pathology …, 2023 - annualreviews.org
Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …

Chimeric antigen receptor T-cells: an overview of concepts, applications, limitations, and proposed solutions

A Alnefaie, S Albogami, Y Asiri, T Ahmad… - … in bioengineering and …, 2022 - frontiersin.org
Adaptive immunity, orchestrated by B-cells and T-cells, plays a crucial role in protecting the
body from pathogenic invaders and can be used as tools to enhance the body's defense …

Cancer treatment and survivorship statistics, 2022

KD Miller, L Nogueira, T Devasia… - CA: a cancer journal …, 2022 - Wiley Online Library
The number of cancer survivors continues to increase in the United States due to the growth
and aging of the population as well as advances in early detection and treatment. To assist …

[HTML][HTML] Dysregulated FOXM1 signaling in the regulation of cancer stem cells

G Sher, T Masoodi, K Patil, S Akhtar… - Seminars in cancer …, 2022 - Elsevier
Since the introduction of the cancer stem cell (CSC) paradigm, significant advances have
been made in understanding the functional and biological plasticity of these elusive …

Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer

Y Bao, J Zhai, H Chen, CC Wong, C Liang, Y Ding… - Gut, 2023 - gut.bmj.com
Objective The role of N6-methyladenosine (m6A) in tumour immune microenvironment
(TIME) remains understudied. Here, we elucidate function and mechanism of YTH N6 …

The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer

JJ Li, JH Wang, T Tian, J Liu, YQ Zheng, HY Mo… - Nature …, 2023 - nature.com
Colorectal cancer (CRC) patients with liver metastases usually obtain less benefit from
immunotherapy, and the underlying mechanisms remain understudied. Here, we identify …