Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health

M Rodriguez-Concepcion, J Avalos, ML Bonet… - Progress in lipid …, 2018 - Elsevier
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic
organisms and some non-photosynthetic prokaryotes and fungi. With some notable …

The nuclear receptor superfamily: A structural perspective

ER Weikum, X Liu, EA Ortlund - Protein Science, 2018 - Wiley Online Library
Nuclear receptors (NRs) are a family of transcription factors that regulate numerous
physiological processes such as metabolism, reproduction, inflammation, as well as the …

Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis

MT Smith, KZ Guyton, CF Gibbons… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: A recent review by the International Agency for Research on Cancer (IARC)
updated the assessments of the> 100 agents classified as Group 1, carcinogenic to humans …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Stress biomarkers in biological fluids and their point-of-use detection

AJ Steckl, P Ray - ACS sensors, 2018 - ACS Publications
Hormones produced by glands in the endocrine system and neurotransmitters produced by
the nervous system control many bodily functions. The concentrations of these molecules in …

Retinoic acid receptors: from molecular mechanisms to cancer therapy

A Di Masi, L Leboffe, E De Marinis, F Pagano… - Molecular aspects of …, 2015 - Elsevier
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

Estrogen receptors: new directions in the new millennium

SC Hewitt, KS Korach - Endocrine reviews, 2018 - academic.oup.com
Nineteen years have passed since our previous review in this journal in 1999 regarding
estrogen receptors. At that time, we described the current assessments of the physiological …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

Vitamin D3: a helpful immuno‐modulator

M Di Rosa, M Malaguarnera, F Nicoletti… - …, 2011 - Wiley Online Library
The active metabolite of vitamin D, 1α, 25‐dihydroxyvitamin D3 [1, 25 (OH) 2D3], is involved
in calcium and phosphate metabolism and exerts a large number of biological effects …