Abstract Cancer-specific TCF1+ stem-like CD8+ T cells can drive protective anticancer
immunity through expansion and effector cell differentiation,,–; however, this response is …

Psoriasis is chronic, immune-mediated, inflammatory disease with a multifactorial etiology
that affects the skin tissue and causes the appearance of dry and scaly lesions of anywhere …

The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is a
promising approach for anti-cancer immunotherapy by bridging innate and adaptive …

Sjögren's syndrome (SjS) is a systemic autoimmune disease marked by xerostomia (dry
mouth), keratoconjunctivitis sicca (eye dryness), and other systematic disorders. Its …

Tumor-infiltrating immune cells (TIICs) are critical players in the tumor microenvironment,
modulating cancer cell functions. TIICs are highly heterogenic and plastic and may either …

The coordination of immunity across organs is fundamental to cancer development and
progression. It is well known that the hostile metabolic microenvironment in the tumour is a …

Stimulation of regulatory T (Treg) cells holds great promise for the treatment of autoimmune,
chronic inflammatory, and certain metabolic diseases. Recent clinical trials with low-dose …

The metabolic reprogramming during T cell activation and differentiation affects T cell fate
and immune responses. Cell metabolism may serve as the driving force that induces …

Since the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), more than 6 million cases are confirmed …

Background Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring
hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are …