Electrical stimulation in bone tissue engineering treatments
L Leppik, KMC Oliveira, MB Bhavsar… - European Journal of …, 2020 - Springer
Electrical stimulation (EStim) has been shown to promote bone healing and regeneration
both in animal experiments and clinical treatments. Therefore, incorporating EStim into …
both in animal experiments and clinical treatments. Therefore, incorporating EStim into …
Three‐dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo
JA Hickman, R Graeser, R de Hoogt… - Biotechnology …, 2014 - Wiley Online Library
Cancers are complex and heterogeneous pathological “organs” in a dynamic interplay with
their host. Models of human cancer in vitro, used in cancer biology and drug discovery, are …
their host. Models of human cancer in vitro, used in cancer biology and drug discovery, are …
Engineering hydrogels as extracellular matrix mimics
Extracellular matrix (ECM) is a complex cellular environment consisting of proteins,
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …
Tissue engineering and regenerative medicine: history, progress, and challenges
F Berthiaume, TJ Maguire… - Annual review of …, 2011 - annualreviews.org
The past three decades have seen the emergence of an endeavor called tissue engineering
and regenerative medicine in which scientists, engineers, and physicians apply tools from a …
and regenerative medicine in which scientists, engineers, and physicians apply tools from a …
[HTML][HTML] Toward exosome-based therapeutics: isolation, heterogeneity, and fit-for-purpose potency
GR Willis, S Kourembanas, SA Mitsialis - Frontiers in cardiovascular …, 2017 - frontiersin.org
Exosomes are defined as submicron (30–150 nm), lipid bilayer-enclosed extracellular
vesicles (EVs), specifically generated by the late endosomal compartment through fusion of …
vesicles (EVs), specifically generated by the late endosomal compartment through fusion of …
Bioprocessing of mesenchymal stem cells and their derivatives: Toward cell‐free therapeutics
Mesenchymal stem cells (MSCs) have attracted tremendous research interest due to their
ability to repair tissues and reduce inflammation when implanted into a damaged or …
ability to repair tissues and reduce inflammation when implanted into a damaged or …
Process engineering of human pluripotent stem cells for clinical application
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
Essential steps in bioprinting: From pre-to post-bioprinting
An increasing demand for directed assembly of biomaterials has inspired the development
of bioprinting, which facilitates the assembling of both cellular and acellular inks into well …
of bioprinting, which facilitates the assembling of both cellular and acellular inks into well …
Scalable stirred-suspension bioreactor culture of human pluripotent stem cells
DE Kehoe, D Jing, LT Lock… - Tissue Engineering Part …, 2010 - liebertpub.com
Advances in stem cell biology have afforded promising results for the generation of various
cell types for therapies against devastating diseases. However, a prerequisite for realizing …
cell types for therapies against devastating diseases. However, a prerequisite for realizing …
Advances in cell culture: anchorage dependence
OW Merten - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …
They represent a formidable production means of viruses for vaccination purposes at very …