Structural and functional aspects of PR‐10 proteins

H Fernandes, K Michalska, M Sikorski… - The FEBS …, 2013 - Wiley Online Library
Physical, chemical and biological stress factors, such as microbial infection, upregulate the
transcription levels of a number of plant genes, coding for the so‐called pathogenesis …

PR10/Bet v1‐like proteins as novel contributors to plant biochemical diversity

JS Morris, KMP Caldo, S Liang, PJ Facchini - ChemBioChem, 2021 - Wiley Online Library
Pathogenesis‐related (PR) proteins constitute a broad class of plant proteins with
analogues found throughout nature from bacteria to higher eukaryotes. PR proteins were …

Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis

SM Christensen, AT Belew, NM El-Sayed… - PLoS neglected …, 2019 - journals.plos.org
Diffuse cutaneous leishmaniasis (DCL) is a rare form of leishmaniasis where parasites grow
uncontrolled in diffuse lesions across the skin. Meta-transcriptomic analysis of biopsies from …

Modulation of IgE reactivity of allergens by site‐directed mutagenesis: potential use of hypoallergenic variants for immunotherapy

F Ferreira, C Ebner, B Kramer, G Casari… - The FASEB …, 1998 - Wiley Online Library
Specific immunotherapy is an efficient treatment for patients suffering from type I allergy. The
mechanisms underlying successful immunotherapy are assumed to operate at the level of T …

Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific …

S Vrtala, K Hirtenlehner, L Vangelista… - The Journal of …, 1997 - Am Soc Clin Investig
A novel approach to reduce the anaphylactic activity of allergens is suggested. The strategy
makes use of the presence of conformational immunoglobulin E (IgE) epitopes on one of the …

Allergic cross-reactivity made visible: solution structure of the major cherry allergen Pru av 1

P Neudecker, K Schweimer, J Nerkamp… - Journal of Biological …, 2001 - ASBMB
Birch pollinosis is often accompanied by hypersensitivity to fruit as a consequence of the
cross-reaction of pollen allergen-specific IgE antibodies with homologous food proteins. To …

Secret of the major birch pollen allergen Bet v 1: identification of the physiological ligand

C Seutter von Loetzen, T Hoffmann, MJ Hartl… - Biochemical …, 2014 - portlandpress.com
The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the PR-10 family (pathogenesis-related proteins 10). Bet v 1 is the most …

The Nuclear Interactor PYL8/RCAR3 of Fagus sylvatica FsPP2C1 Is a Positive Regulator of Abscisic Acid Signaling in Seeds and Stress

X Saavedra, A Modrego, D Rodriݩguez… - Plant …, 2010 - academic.oup.com
The functional protein phosphatase type 2C from beechnut (Fagus sylvatica; FsPP2C1) was
a negative regulator of abscisic acid (ABA) signaling in seeds. In this report, to get deeper …

High pressure, thermal and pulsed electric‐field‐induced structural changes in selected food allergens

PE Johnson, I Van der Plancken… - Molecular nutrition & …, 2010 - Wiley Online Library
Scope: The effects of high‐pressure/temperature treatment and pulsed electric field
treatment on native peanut Ara h 2, 6 and apple Mal d 3 and Mal d 1b prepared by …

Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice

I Schöll, N Kalkura, Y Shedziankova… - The Journal of …, 2005 - journals.aai.org
In type I allergy, the cross-linking of membrane IgE on B lymphocytes and of cytophilic IgE
on effector cells by their respective allergens are key events. For cross-linking two IgE …