[HTML][HTML] Extracellular vesicles: New classification and tumor immunosuppression
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
[HTML][HTML] Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives
The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …
dysregulation of the metabolic pathways of these molecules is implicated in various acute …
[PDF][PDF] Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
D Lv, X Cao, L Zhong, Y Dong, Z Xu, Y Rong, H Xu… - Cell Reports …, 2023 - cell.com
Moderate inflammation is essential for standard wound healing. In pathological conditions,
such as diabetes, protracted and refractory wounds are associated with excessive …
such as diabetes, protracted and refractory wounds are associated with excessive …
[HTML][HTML] Molecular mechanism of palmitic acid and its derivatives in tumor progression
X Wang, C Zhang, N Bao - Frontiers in oncology, 2023 - ncbi.nlm.nih.gov
Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …
serves as an energy source for the body and plays a role in the structure and function of cell …
Mechanisms and functions of protein S-acylation
F S. Mesquita, L Abrami, ME Linder, SX Bamji… - … Reviews Molecular Cell …, 2024 - nature.com
Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has
emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible …
emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible …
AMPKα1-mediated ZDHHC8 phosphorylation promotes the palmitoylation of SLC7A11 to facilitate ferroptosis resistance in glioblastoma
Z Wang, Y Wang, N Shen, Y Liu, X Xu, R Zhu, H Jiang… - Cancer Letters, 2024 - Elsevier
The cystine/glutamate antiporter SLC7A11, as the key regulator of ferroptosis, functions to
transport cystine for glutathione biosynthesis and antioxidant defense. Accumulating …
transport cystine for glutathione biosynthesis and antioxidant defense. Accumulating …
[HTML][HTML] The palmitoylation of AEG-1 dynamically modulates the progression of hepatocellular carcinoma
B Zhou, Y Wang, L Zhang, X Shi, H Kong, M Zhang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Protein palmitoylation is tightly related to tumorigenesis or tumor progression as
many oncogenes or tumor suppressors are palmitoylated. AEG-1, an oncogene, is …
many oncogenes or tumor suppressors are palmitoylated. AEG-1, an oncogene, is …
[HTML][HTML] The role of E3 ubiquitin ligases and deubiquitinases in bladder cancer development and immunotherapy
X Wang, Y Zhang, Y Wu, H Cheng, X Wang - Frontiers in Immunology, 2023 - frontiersin.org
Bladder cancer is one of the common malignant urothelial tumors. Post-translational
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …
Palmitoylation of solute carriers
CE Villanueva, B Hagenbuch - Biochemical pharmacology, 2023 - Elsevier
Post-translational modifications are an important mechanism in the regulation of protein
expression, function, and degradation. Well-known post-translational modifications are …
expression, function, and degradation. Well-known post-translational modifications are …
[HTML][HTML] Lymphoma in Border Collies: Genome-Wide Association and Pedigree Analysis
PXY Soh, MS Khatkar, P Williamson - Veterinary Sciences, 2023 - mdpi.com
Simple Summary Lymphoma is a common cancer in dogs, with large variation between
breeds in both the incidence and frequency of immunophenotypes (B-cell or T-cell …
breeds in both the incidence and frequency of immunophenotypes (B-cell or T-cell …