[HTML][HTML] Extracellular vesicles: New classification and tumor immunosuppression

M Sheta, EA Taha, Y Lu, T Eguchi - Biology, 2023 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …

[HTML][HTML] Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives

YH Yang, R Wen, N Yang, TN Zhang, CF Liu - Molecular medicine, 2023 - Springer
The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …

[PDF][PDF] Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

D Lv, X Cao, L Zhong, Y Dong, Z Xu, Y Rong, H Xu… - Cell Reports …, 2023 - cell.com
Moderate inflammation is essential for standard wound healing. In pathological conditions,
such as diabetes, protracted and refractory wounds are associated with excessive …

[HTML][HTML] Molecular mechanism of palmitic acid and its derivatives in tumor progression

X Wang, C Zhang, N Bao - Frontiers in oncology, 2023 - ncbi.nlm.nih.gov
Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …

Mechanisms and functions of protein S-acylation

F S. Mesquita, L Abrami, ME Linder, SX Bamji… - … Reviews Molecular Cell …, 2024 - nature.com
Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has
emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible …

AMPKα1-mediated ZDHHC8 phosphorylation promotes the palmitoylation of SLC7A11 to facilitate ferroptosis resistance in glioblastoma

Z Wang, Y Wang, N Shen, Y Liu, X Xu, R Zhu, H Jiang… - Cancer Letters, 2024 - Elsevier
The cystine/glutamate antiporter SLC7A11, as the key regulator of ferroptosis, functions to
transport cystine for glutathione biosynthesis and antioxidant defense. Accumulating …

[HTML][HTML] The palmitoylation of AEG-1 dynamically modulates the progression of hepatocellular carcinoma

B Zhou, Y Wang, L Zhang, X Shi, H Kong, M Zhang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Protein palmitoylation is tightly related to tumorigenesis or tumor progression as
many oncogenes or tumor suppressors are palmitoylated. AEG-1, an oncogene, is …

[HTML][HTML] The role of E3 ubiquitin ligases and deubiquitinases in bladder cancer development and immunotherapy

X Wang, Y Zhang, Y Wu, H Cheng, X Wang - Frontiers in Immunology, 2023 - frontiersin.org
Bladder cancer is one of the common malignant urothelial tumors. Post-translational
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …

Palmitoylation of solute carriers

CE Villanueva, B Hagenbuch - Biochemical pharmacology, 2023 - Elsevier
Post-translational modifications are an important mechanism in the regulation of protein
expression, function, and degradation. Well-known post-translational modifications are …

[HTML][HTML] Lymphoma in Border Collies: Genome-Wide Association and Pedigree Analysis

PXY Soh, MS Khatkar, P Williamson - Veterinary Sciences, 2023 - mdpi.com
Simple Summary Lymphoma is a common cancer in dogs, with large variation between
breeds in both the incidence and frequency of immunophenotypes (B-cell or T-cell …