[HTML][HTML] Risk stratification and medical therapy of pulmonary arterial hypertension

N Galiè, RN Channick, RP Frantz… - European …, 2019 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) remains a severe clinical condition despite the
availability over the past 15 years of multiple drugs interfering with the endothelin, nitric …

Heart disease and stroke statistics—2018 update: a report from the American Heart Association

EJ Benjamin, SS Virani, CW Callaway… - Circulation, 2018 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Pulmonary hypertension

A Mocumbi, M Humbert, A Saxena, ZC Jing… - Nature Reviews …, 2024 - nature.com
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …

Pulmonary arterial hypertension: pathogenesis and clinical management

T Thenappan, ML Ormiston, JJ Ryan, SL Archer - Bmj, 2018 - bmj.com
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

[PDF][PDF] 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

N Galiè, M Humbert, JL Vachiery… - Polish Heart …, 2015 - journals.viamedica.pl
6.2. 2. Wydolność wysiłkowa......................... 1147 6.2. 3. Markery biochemiczne........................
1147 6.2. 4. Kompleksowa ocena rokownicza i oszacowanie ryzyka........................... 1148 6.2 …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

A global view of pulmonary hypertension

MM Hoeper, M Humbert, R Souza, M Idrees… - The Lancet …, 2016 - thelancet.com
Pulmonary hypertension is a substantial global health issue. All age groups are affected with
rapidly growing importance in elderly people, particularly in countries with ageing …

Selexipag for the treatment of pulmonary arterial hypertension

O Sitbon, R Channick, KM Chin, A Frey… - … England Journal of …, 2015 - Mass Medical Soc
Background In a phase 2 trial, selexipag, an oral selective IP prostacyclin-receptor agonist,
was shown to be beneficial in the treatment of pulmonary arterial hypertension. Methods In …

Initial use of ambrisentan plus tadalafil in pulmonary arterial hypertension

N Galiè, JA Barberà, AE Frost… - … England Journal of …, 2015 - Mass Medical Soc
Background Data on the effect of initial combination therapy with ambrisentan and tadalafil
on long-term outcomes in patients with pulmonary arterial hypertension are scarce. Methods …

Epidemiology and treatment of pulmonary arterial hypertension

EMT Lau, E Giannoulatou, DS Celermajer… - Nature Reviews …, 2017 - nature.com
In the past 2 decades, major changes have occurred in the epidemiological and treatment
landscape of pulmonary arterial hypertension (PAH). Previously regarded as a disease of …