Hybrid graphene oxide based plasmonic-magnetic multifunctional nanoplatform for selective separation and label-free identification of Alzheimer's disease …

T Demeritte, BP Viraka Nellore… - … applied materials & …, 2015 - ACS Publications
Despite intense efforts, Alzheimer's disease (AD) is one of the top public health crisis for
society even at 21st century. Since presently there is no cure for AD, early diagnosis of …

Near‐Infrared Bodipy‐Based Molecular Rotors for β‐Amyloid Imaging In Vivo

L Ma, Y Geng, G Zhang, Z Hu, TD James… - Advanced …, 2023 - Wiley Online Library
Abstract β‐amyloid (Aβ) is one of the important biomarkers for diagnosing Alzheimer's
disease (AD). Many near‐infrared probes based on the donor‐π‐acceptor structure have …

Efficient inhibition of protein aggregation, disintegration of aggregates, and lowering of cytotoxicity by green tea polyphenol-based self-assembled polymer …

K Debnath, S Shekhar, V Kumar… - ACS applied materials …, 2016 - ACS Publications
Green tea polyphenol epigallocatechin-3-gallate (EGCG) is known for its antiamyloidogenic
property, and it is observed that molecular EGCG binds with amyloid structure, redirects …

[HTML][HTML] Neurotheranostics as personalized medicines

BD Kevadiya, BM Ottemann, MB Thomas… - Advanced Drug Delivery …, 2019 - Elsevier
The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions

R Sandhir, A Yadav, A Sunkaria, N Singhal - Neurochemistry international, 2015 - Elsevier
Oxidative stress has for long been linked to the neuronal cell death in many
neurodegenerative conditions. Conventional antioxidant therapies have been less effective …

Microfluidic synthesis of ultrasmall chitosan/graphene quantum dots particles for intranasal delivery in Alzheimer's disease treatment

F Mohebichamkhorami, M Faizi, M Mahmoudifard… - Small, 2023 - Wiley Online Library
Nanoparticles (NPs) based therapies for Alzheimer's disease (AD) attract interest due to
their ability to pass across or bypass the blood‐brain barrier. Chitosan (CS) NPs or …

New frontiers in molecular imaging with superparamagnetic iron oxide nanoparticles (SPIONs): efficacy, toxicity, and future applications

V Frantellizzi, M Conte, M Pontico, A Pani… - Nuclear medicine and …, 2020 - Springer
Abstract Supermagnetic Iron Oxide Nanoparticles (SPIONs) are nanoparticles that have an
iron oxide core and a functionalized shell. SPIONs have recently raised much interest in the …

[HTML][HTML] Nanomedicine-based immunotherapy for central nervous system disorders

S Hanif, P Muhammad, R Chesworth… - Acta Pharmacologica …, 2020 - nature.com
Central nervous system (CNS) disorders represent a broad spectrum of brain ailments with
short-and long-term disabilities, and nanomedicine-based approaches provide a new …

Design, synthesis, and evaluation of orally bioavailable quinoline–indole derivatives as innovative multitarget-directed ligands: Promotion of cell proliferation in the …

Z Wang, J Hu, X Yang, X Feng, X Li… - Journal of Medicinal …, 2018 - ACS Publications
A novel series of quinoline–indole derivatives were synthesized and evaluated as
multitarget-directed ligands for the treatment of Alzheimer's disease (AD). Biological …

Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer's Disease in Mice, Observed by in Vivo Two-Photon Imaging

D Kim, SH Baik, S Kang, SW Cho, J Bae… - ACS central …, 2016 - ACS Publications
Monoamine oxidases (MAOs) play an important role in Alzheimer's disease (AD) pathology.
We report in vivo comonitoring of MAO activity and amyloid-β (Aβ) plaques dependent on …