A Review on the Ethnopharmacology and Phytochemistry of the Neotropical Sages (Salvia Subgenus Calosphace; Lamiaceae) Emphasizing Mexican Species

N Ortiz-Mendoza, E Aguirre-Hernández… - Frontiers in …, 2022 - frontiersin.org
Salvia is the most diverse genus within the mint family (Lamiaceae), many of its species are
well-known due to their medicinal and culinary uses. Most of the ethnopharmacological and …

Lamiaceae in Mexican species, a great but scarcely explored source of secondary metabolites with potential pharmacological effects in pain relief

A Hernandez-Leon, GF Moreno-Pérez… - Molecules, 2021 - mdpi.com
The search for molecules that contribute to the relief of pain is a field of research in constant
development. Lamiaceae is one of the most recognized families world-wide for its use in …

Uncommon Terpenoids from Salvia Species: Chemistry, Biosynthesis and Biological Activities

S Hafez Ghoran, F Taktaz, AA Mozafari, M Tunçtürk… - Molecules, 2022 - mdpi.com
The search for new bioactive compounds from plant sources has been and continues to be
one of the most important fields of research in drug discovery. However, Natural Products …

Flupirtine and antihistamines exert synergistic anti-nociceptive effects in mice

Y Chen, X Xiao, C Huang, J Zhu, H Zhou, H Qin… - …, 2023 - Springer
Rationale Drug combinations are commonly used in pain management, which can produce
potent analgesic effects with reduced dosage and adverse effects. Objective This study was …

Antihyperalgesic and Antiallodynic Effects of Amarisolide A and Salvia amarissima Ortega in Experimental Fibromyalgia-Type Pain

GF Moreno-Pérez, ME González-Trujano… - Metabolites, 2022 - mdpi.com
Salvia amarissima Ortega is an endemic species of Mexico used in folk medicine to alleviate
pain and as a nervous tranquilizer. The S. amarissima extract and one of its abundant …

[HTML][HTML] Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice

R Mendoza-Madrigal, ME González-Trujano… - Biomedicine & …, 2024 - Elsevier
Salvia amarissima Ortega is a plant used in traditional medicine to treat CNS's affections.
Despite its depressant properties in anxiety and fibromyalgia, there is no scientific evidence …

[HTML][HTML] Antinociceptive effect of Mansoa alliacea polar extracts involves opioid receptors and nitric oxide in experimental nociception in mice

MG Valle-Dorado, A Hernández-León… - Biomedicine & …, 2022 - Elsevier
To evaluate the antinociceptive effect and the possible mechanism of action of two polar
extracts of Mansoa alliacea, a medicinal plant used in Perú, Brazil, and Mexico to treat …

Novel drug-drug salt crystals of metformin with ibuprofen or naproxen: Improved solubility, dissolution rate, and synergistic antinociceptive effects

HM Qin, ZK Luo, HL Zhou, J Zhu, XY Xiao… - International Journal of …, 2024 - Elsevier
As the monotherapy of available analgesics is usually accompanied by serious side effects
or limited efficacy in the management of chronic pain, multimodal analgesia is widely used …

Plant and Growth Condition Interactions on the Phenolic Compound Contents and Antioxidant Activity in Salvia circinata Cav., a Medicinal Sage

ML Pérez-Ochoa, AM Vera-Guzmán… - Diversity, 2023 - mdpi.com
The genus Salvia has a worldwide distribution, and its contribution to traditional medicine
and as an aromatic plant has been recognized since ancient times, with few documented …

Amarisolide H and 15-epi-Amarisolide H, Two Diterpenoid Glucosides from Salvia circinnata

X García-Nava, M Fragoso-Serrano, E Bautista… - Revista Brasileira de …, 2022 - Springer
The HPLC–PDA profiling of an acetone-soluble extract of the leaves of Salvia circinnata
Cav.(Syn. Salvia amarissima Ortega), Lamiaceae, collected at Patzcuaro, Michoacan …