T-follicular helper (Tfh) cells are key drivers of antibodies that protect from malaria. However,
little is known regarding the host and parasite factors that influence Tfh and functional …

Capsid-like particles (CLPs) are multimeric, repetitive assemblies of recombinant viral
capsid proteins, which are highly immunogenic due to their structural similarity to wild-type …

It is obvious that there is a critical need for an efficient malaria vaccine to accelerate malaria
eradication. Currently, recombinant subunit vaccination against malaria using proteins and …

Understanding how immunity to malaria is affected by declining transmission is important to
aid vaccine design and understand disease resurgence. Both IgG subclasses and avidity of …

During its life cycle, Plasmodium, the malaria parasite, is exposed to the human and
mosquito complement systems. Early experiments demonstrated that activation of …

Recent malaria vaccine trials in endemic areas have yielded disparate results compared to
studies conducted in non-endemic areas. A workshop was organized to discuss the …

Malaria burden has significantly changed or decreased over the last 20 years, however, it
remains an important health problem requiring the rigorous application of existing tools and …

Background Antibody-driven complement system (CS) activation has been associated with
protection against symptomatic dengue virus (DENV) infection. Aggregation, opsonization …

Plasmodium falciparum (P. falciparum) is a leading causative agent of malaria, an infectious
disease that can be fatal. Unfortunately, control measures are becoming less effective over …

Malaria is a severe human disease and a global health problem because of drug-resistant
strains. Drugs reported to prevent the growth of Plasmodium parasites target various phases …