Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of …
S Piawah, AP Venook - Cancer, 2019 - Wiley Online Library
Despite recent advances in the management of colorectal cancer, metastatic disease
remains challenging, and patients are rarely cured. However, a better understanding of the …
remains challenging, and patients are rarely cured. However, a better understanding of the …
Prevalence, prognosis and predictive status of HER2 amplification in anti-EGFR-resistant metastatic colorectal cancer
G Wang, Y He, Y Sun, W Wang, X Qian, X Yu… - Clinical and Translational …, 2020 - Springer
Numerous inherent and acquired genetic alterations have been demonstrated with
resistance to anti-epidermal growth factor receptor (anti-EGFR) therapy in metastatic …
resistance to anti-epidermal growth factor receptor (anti-EGFR) therapy in metastatic …
Tumor-associated microbiota in proximal and distal colorectal cancer and their relationships with clinical outcomes
M Jin, F Shang, J Wu, Q Fan, C Chen, J Fan… - Frontiers in …, 2021 - frontiersin.org
The proximal and distal subsites of colorectal cancer (CRC) have distinct differences in their
embryonic origin, epidemiology, and prognosis. Therefore, they are not considered as the …
embryonic origin, epidemiology, and prognosis. Therefore, they are not considered as the …
Development and external validation of a multiparametric MRI-based radiomics model for preoperative prediction of microsatellite instability status in rectal cancer: a …
Z Li, J Zhang, Q Zhong, Z Feng, Y Shi, L Xu… - European …, 2023 - Springer
Objectives To establish and validate a radiomics model based on multiparametric magnetic
resonance imaging (MRI), and to predict microsatellite instability (MSI) status in rectal cancer …
resonance imaging (MRI), and to predict microsatellite instability (MSI) status in rectal cancer …
Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin is mediated by targeting the Akt signaling pathway and activating the Hippo signaling …
D Hu, RY Meng, TV Nguyen… - Molecular …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the deadliest malignant tumors worldwide and its
prevalence is increasing in South Korea. The efficacy of combined treatment with natural …
prevalence is increasing in South Korea. The efficacy of combined treatment with natural …
Associations of vitamin D status with colorectal cancer risk and survival
J Zhou, X Ge, X Fan, J Wang, L Miao… - International journal of …, 2021 - Wiley Online Library
Biological evidence suggests that vitamin D has numerous anticancer functions, but the
associations between vitamin D status and colorectal cancer (CRC) risk and survival remain …
associations between vitamin D status and colorectal cancer (CRC) risk and survival remain …
Racial disparities in epigenetic aging of the right vs left colon
There are well-documented racial differences in age-of-onset and laterality of colorectal
cancer. Epigenetic age acceleration is postulated to be an underlying factor. However …
cancer. Epigenetic age acceleration is postulated to be an underlying factor. However …
Alterations of circulating lymphocyte subsets in patients with colorectal carcinoma
J Waidhauser, P Nerlinger, TT Arndt, S Schiele… - Cancer Immunology …, 2022 - Springer
Introduction Cellular immune response to cancer is known to be of great importance for
tumor control. Moreover, solid tumors influence circulating lymphocytes, which has been …
tumor control. Moreover, solid tumors influence circulating lymphocytes, which has been …
HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/β-catenin axis in right-sided colon cancer
L Qi, J Chen, B Zhou, K Xu, K Wang, Z Fang… - Cell death & …, 2021 - nature.com
Patients with right-sided colon cancer (RCC) generally have a poorer prognosis than those
with left-sided colon cancer (LCC). We previously found that homeobox C6 (HOXC6) was …
with left-sided colon cancer (LCC). We previously found that homeobox C6 (HOXC6) was …
Prognostic significance of laterality in lung neuroendocrine tumors
A La Salvia, I Persano, A Siciliani, M Verrico, M Bassi… - Endocrine, 2022 - Springer
Purpose: Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical
(TC) and atypical (AC) carcinoids, based on mitotic counts and necrosis. However …
(TC) and atypical (AC) carcinoids, based on mitotic counts and necrosis. However …