Asthma in Latin America: a public heath challenge and research opportunity

PJ Cooper, LC Rodrigues, AA Cruz, ML Barreto - Allergy, 2009 - Wiley Online Library
Asthma has emerged as an important public health problem in many Latin American
countries over the past decade. In Brazil and Costa Rica, the prevalence of asthma and …

Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme

PJ Cooper, CA Figueiredo, A Rodriguez… - Clinical and …, 2023 - Wiley Online Library
Asthma is an important health concern in Latin America (LA) where it is associated with
variable prevalence and disease burden between countries. High prevalence and morbidity …

[HTML][HTML] Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity

IE Mulder, B Schmidt, M Lewis, M Delday, CR Stokes… - PloS one, 2011 - journals.plos.org
Background Acquisition of the intestinal microbiota in early life corresponds with the
development of the mucosal immune system. Recent work on caesarean-delivered infants …

Urbanisation is associated with prevalence of childhood asthma in diverse, small rural communities in Ecuador

A Rodriguez, M Vaca, G Oviedo, S Erazo, ME Chico… - Thorax, 2011 - thorax.bmj.com
Background Studies conducted in transitional communities from Africa and Asia have
pointed to the process of urbanisation as being responsible for the increase in asthma …

[HTML][HTML] Estimating adjusted prevalence ratio in clustered cross-sectional epidemiological data

CAST Santos, RL Fiaccone, NF Oliveira… - BMC Medical Research …, 2008 - Springer
Background Many epidemiologic studies report the odds ratio as a measure of association
for cross-sectional studies with common outcomes. In such cases, the prevalence ratios may …

Risk factors for atopic and non-atopic asthma in a rural area of Ecuador

AL Moncayo, M Vaca, G Oviedo, S Erazo, I Quinzo… - Thorax, 2010 - thorax.bmj.com
Background Asthma has emerged as an important public health problem of urban
populations in Latin America. Epidemiological data suggest that a minority of asthma cases …

Longterm periodic anthelmintic treatments are associated with increased allergen skin reactivity

P Endara, M Vaca, ME Chico, S Erazo… - Clinical & …, 2010 - Wiley Online Library
Background The low prevalence of allergic disease in the rural tropics has been attributed to
the protective effects of chronic helminth infections. There is concern that treatmentbased …

[HTML][HTML] Impact of long-term treatment with ivermectin on the prevalence and intensity of soil-transmitted helminth infections

AL Moncayo, M Vaca, L Amorim… - PLoS neglected …, 2008 - journals.plos.org
Background Control of soil-transmitted helminth (STH) infections relies on the periodic and
long-term administration of anthelmintic drugs to high-risk groups, particularly school-age …

Hygiene, atopy and wheeze–eczema–rhinitis symptoms in schoolchildren from urban and rural Ecuador

PJ Cooper, M Vaca, A Rodriguez, ME Chico… - Thorax, 2014 - thorax.bmj.com
Background Rural residence is protective against atopy and wheeze–rhinitis–eczema
symptoms in developed countries, an effect attributed to farming and poor hygiene …

[HTML][HTML] Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune …

R Teran, E Mitre, M Vaca, S Erazo, G Oviedo… - Clinical …, 2011 - Elsevier
The immune response that develops in early childhood underlies the development of
inflammatory diseases such as asthma and there are few data from tropical Latin America …