Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently,
compelling evidence has arisen for the role of monocytes and neutrophils and a particular …

The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …

Atherosclerosis contributes to the development of many cardiovascular diseases, which
remain the leading cause of death in developed countries. Atherosclerosis is a chronic …

Lutein is a xanthophyll carotenoid obtained from various foods, such as dark green leafy
vegetables and egg yolk. Lutein has antioxidant activity and scavenges reactive oxygen …

Objective—Although the role of monocytes in the pathogenesis of atherosclerosis is well
established, the persistent vascular inflammation remains largely unexplained. Recently, our …

Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

Complex interactions exist between cytokines and the interleukin family plays a fundamental
role in inflammation. Particularly circulating IL-1β, IL-6 and IL-8 are unregulated in systemic …

The beneficial effects of a Mediterranean diet on human health and, in particular, on
lowering risk of cardiovascular disease, has been mainly attributed to its high content to …

Smooth muscle cells (SMCs) possess remarkable phenotypic plasticity that allows rapid
adaptation to fluctuating environmental cues, including during development and progression …

Background The global population of older individuals is growing, and ageing is a key risk
factor for atherosclerotic cardiovascular diseases. Abnormal accumulation of senescent cells …