[HTML][HTML] Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

H Gylling, J Plat, S Turley, HN Ginsberg, L Ellegård… - Atherosclerosis, 2014 - Elsevier
Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

Inflammation as a therapeutic target in atherosclerosis

MT Nguyen, S Fernando, N Schwarz, JTM Tan… - Journal of clinical …, 2019 - mdpi.com
Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

Origin and physiological roles of inflammation

R Medzhitov - Nature, 2008 - nature.com
Inflammation underlies a wide variety of physiological and pathological processes. Although
the pathological aspects of many types of inflammation are well appreciated, their …

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

X Li, P Fang, J Mai, ET Choi, H Wang… - Journal of hematology & …, 2013 - Springer
There are multiple sources of reactive oxygen species (ROS) in the cell. As a major site of
ROS production, mitochondria have drawn considerable interest because it was recently …

Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society

L Zanoli, M Briet, JP Empana, PG Cunha… - Journal of …, 2020 - journals.lww.com
Inflammation is a physiological response to aggression of pathogenic agents aimed at
eliminating the aggressor agent and promoting healing. Excessive inflammation, however …

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

K Rajamäki, J Lappalainen, K Öörni, E Välimäki… - PloS one, 2010 - journals.plos.org
Background Chronic inflammation of the arterial wall is a key element in the pathogenesis of
atherosclerosis, yet the factors that trigger and sustain the inflammation remain elusive …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Extra virgin olive oil: More than a healthy fat

EM Yubero-Serrano, J Lopez-Moreno… - European journal of …, 2019 - nature.com
The beneficial effects of a Mediterranean diet on human health and, in particular, on
lowering risk of cardiovascular disease, has been mainly attributed to its high content to …

Inflammatory cytokines in vascular dysfunction and vascular disease

AH Sprague, RA Khalil - Biochemical pharmacology, 2009 - Elsevier
The vascular inflammatory response involves complex interaction between inflammatory
cells (neutrophils, lymphocytes, monocytes, macrophages), endothelial cells (ECs), vascular …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …