Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm …

Background—Cardiovascular disease is the leading cause of death among those with
diabetes mellitus. Vitamin D deficiency is associated with an increased risk of cardiovascular …

Adipose tissue depots originate from distinct precursor cells, are functionally diverse, and
modulate disease processes in a depot-specific manner. However, the functional properties …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Loneliness is a predictor of mortality and increased cardiovascular morbidity. Inflammation is
a potential pathway through which loneliness might impact health. The aim of the study was …

Matrix metalloproteinases (MMPs) can degrade strength-giving collagens and other
structural proteins of the arterial extracellular matrix. Overproduction of MMPs by monocyte …

Background—Although the participation of inflammation in atherogenesis is widely
recognized, the identification of the different components has not been clarified. In particular …

Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …

Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

In many ways, atherosclerosis is a chronic inflammatory disorder and this issue is confirmed
by recent investigations of that have focused on inflammation, providing new insight into …