Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Objectives Chemerin is a recently discovered adipokine that regulates adipocyte
differentiation and modulates chemotaxis and activation of dendritic cells and macrophages …

It remains unknown whether newly identified anti-inflammatory/immunosuppressive cytokine
interleukin-35 (IL-35) is different from other anti-inflammatory cytokines such as IL-10 and …

The let-7 miRNA family plays a key role in modulating inflammatory responses. Vascular
smooth muscle cell (SMC) proliferation and endothelial cell (EC) dysfunction are critical in …

Objective—To score the number of plaque neutrophils and relate the score to plaque
morphology and inflammatory status. Methods and Results—Neutrophils are inflammatory …

Visfatin has recently been identified as a novel visceral adipokine which may be involved in
obesity-related vascular disorders. However, it is not known whether visfatin directly …

Atherosclerosis is a chronic progressive inflammatory disease of the large and medium-
sized artery walls. The molecular mechanisms regulating the onset and progression of …

Inflammation is a classical host defence response to infection and injury that has many
beneficial effects. However, inappropriate (in time, place and magnitude) inflammation is …

Emerging epidemiological evidence suggests that exposure to particulate matter (PM) air
pollution increases the risk of cardiovascular events but the exact mechanism by which PM …