Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

[HTML][HTML] The role of European healthcare databases for post-marketing drug effectiveness, safety and value evaluation: where does Italy stand?

G Trifirò, R Gini, F Barone-Adesi, E Beghi, A Cantarutti… - Drug Safety, 2019 - Springer
Enormous progress has been made globally in the use of evidence derived from patients'
clinical information as they access their routine medical care. The value of real-world data …

The dose of inhaled corticosteroids in patients with COPD: when less is better

JL Izquierdo, BG Cosio - International Journal of Chronic …, 2018 - Taylor & Francis
Background The use of inhaled corticosteroids (ICS) in combination with bronchodilators in
patients with COPD has been shown to decrease the rate of disease exacerbations and to …

[HTML][HTML] Reducing the risk of mortality in chronic obstructive pulmonary disease with pharmacotherapy: A narrative review

M Mintz, I Barjaktarevic, DA Mahler, B Make… - Mayo Clinic …, 2023 - Elsevier
In 2020, chronic obstructive pulmonary disease (COPD) was the fifth leading cause of death
in the United States excluding COVID-19, and its mortality burden has been rising since the …

The impact of adherence to inhaled drugs on 5‐year survival in COPD patients: a time dependent approach

V Belleudi, M Di Martino, S Cascini… - … and drug safety, 2016 - Wiley Online Library
Purpose Whether inhaled medications improve long‐term survival in Chronic Obstructive
Pulmonary Disease (COPD) is an open question. The purpose of this study is to assess the …

Chronic obstructive pulmonary disease: moving from symptom relief to mortality reduction

A Celi, M Latorre, P Paggiaro… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Chronic obstructive pulmonary disease (COPD) has a 3-year mortality rate up to 37%, 2–6
times higher than the general population. We present evidence supporting pharmacological …

Fluticasone propionate/formoterol for COPD management: a randomized controlled trial

A Papi, D Dokic, W Tzimas, I Mészáros… - … journal of chronic …, 2017 - Taylor & Francis
Purpose To evaluate fluticasone propionate/formoterol (FP/FORM) in COPD. Patients and
methods COPD patients with forced expiratory volume in 1 s (FEV1)≤ 50% predicted and≥ …

[HTML][HTML] GOLD 2017 recommendations for COPD patients: toward a more personalized approach

S Roversi, L Corbetta, E Clini - COPD Research and Practice, 2017 - Springer
Abstract The Global Initiative for Chronic Obstructive Lung Disease (GOLD), an international
committee of experts, has recently published its updated report on diagnosis and …

[HTML][HTML] Triple therapy in COPD: can we welcome the reduction in cardiovascular risk and mortality?

P Solidoro, C Albera, F Ribolla, M Bellocchia… - Frontiers in …, 2022 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a complex disease which consists in the
reduction of the airflow and leads to the disruption of the pulmonary tissue due to a chronic …

Observational studies of inhaled corticosteroid effectiveness in COPD: lessons learned

S Suissa, P Ernst - Chest, 2018 - Elsevier
Background Randomized controlled trials at times investigate findings suggested by
observational studies. For example, the Towards a Revolution in COPD Health (TORCH) …