Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model-are we there yet?
E Jesulola, P Micalos, IJ Baguley - Behavioural brain research, 2018 - Elsevier
A number of factors (biogenic amine deficiency, genetic, environmental, immunologic,
endocrine factors and neurogenesis) have been identified as mechanisms which provide …
endocrine factors and neurogenesis) have been identified as mechanisms which provide …
Drug repurposing in cancer
L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …
increase in the coming years. Whereas the limited success with current therapies has driven …
[HTML][HTML] Understanding the complex of suicide in depression: from research to clinics
L Orsolini, R Latini, M Pompili, G Serafini… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Amongst psychiatric disorders, major depressive disorder (MDD) is the most
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …
[HTML][HTML] The role of BDNF on neural plasticity in depression
T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …
depression is closely related to the abnormal neural plasticity processes occurring in the …
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
INTRODUCTION Depression is an episodic form of mental illness, yet the circuit-level
mechanisms driving the induction, remission, and recurrence of depressive episodes over …
mechanisms driving the induction, remission, and recurrence of depressive episodes over …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
[HTML][HTML] Major depression: one brain, one disease, one set of intertwined processes
EV Filatova, MI Shadrina, PA Slominsky - Cells, 2021 - mdpi.com
Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …
[HTML][HTML] Pharmacological treatment of anxiety disorders: the role of the HPA axis
GE Tafet, CB Nemeroff - Frontiers in psychiatry, 2020 - frontiersin.org
Stress in general, and early life stress in particular, has been associated with the
development of anxiety and mood disorders. The molecular, biological and psychological …
development of anxiety and mood disorders. The molecular, biological and psychological …
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
Recent studies suggest that stress-induced atrophy and loss of hippocampal neurons may
contribute to the pathophysiology of depression. The aim of this study was to investigate the …
contribute to the pathophysiology of depression. The aim of this study was to investigate the …
[图书][B] A clinical guide to the treatment of the human stress response
SG Everly, M Lating Jr - 2019 - Springer
A Clinical Guide to the Treatment of the Human Stress Response Page 1 George S. Everly,
Jr. · Jeffrey M. Lating A Clinical Guide to the Treatment of the Human Stress Response …
Jr. · Jeffrey M. Lating A Clinical Guide to the Treatment of the Human Stress Response …