Gene therapy represents an innovative and promising alternative for the treatment of
epileptic patients who are resistant to conventional antiepileptic drugs. Among the various …

The ketogenic diet (KD) is a high‐fat, low‐carbohydrate, low‐protein diet used to treat
refractory epilepsy. Despite its efficacy and many years of investigation, the mechanism by …

Childhood epilepsies comprise a heterogeneous group of disorders and syndromes that
vary in terms of severity, prognosis and treatment requirements. Effective management …

Purpose: Neuropeptides and neurotrophic factors are thought to be involved in
epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs …

Studies in both humans and rodents suggest that exercise can be neuroprotective, but the
mechanisms by which this occurs are still poorly understood. Three weeks of voluntary …

Introduction: Galanin is a 29/30 amino acid long neuropeptide that is widely expressed in
the brains of many mammals. Galanin exerts its biological activities through three different G …

The pituitary is the central endocrine gland that regulates the functions of various target
organs in the human body. Because of the pivotal regulatory role of the pituitary, it is …

Adenosine is an endogenous anticonvulsant that is controlled by an astrocyte-based
adenosine cycle and expression levels of its key negative regulator adenosine kinase …

Galanin, a neuropeptide widely expressed in the central and peripheral nervous systems
and in the endocrine system, has been shown to regulate numerous physiological and …

Epileptic seizure activity manifests as complex spatio‐temporal dynamics on the clinically
relevant macroscopic scale. These dynamics are known to arise from spatially …