Application of electronic-nose technologies and VOC-biomarkers for the noninvasive early diagnosis of gastrointestinal diseases

AD Wilson - Sensors, 2018 - mdpi.com
Conventional methods utilized for clinical diagnosis of gastrointestinal (GI) diseases have
employed invasive medical procedures that cause stress, anxiety and pain to patients …

Applications of electronic-nose technologies for noninvasive early detection of plant, animal and human diseases

AD Wilson - Chemosensors, 2018 - mdpi.com
The development of electronic-nose (e-nose) technologies for disease diagnostics was
initiated in the biomedical field for detection of biotic (microbial) causes of human diseases …

Towards novel non-invasive colorectal cancer screening methods: a comprehensive review

A Ferrari, I Neefs, S Hoeck, M Peeters, G Van Hal - Cancers, 2021 - mdpi.com
Simple Summary Since the 70s, a variety of colorectal cancer (CRC) screening programs
have been adopted throughout the world with the aim of reducing the mortality rate of one of …

[HTML][HTML] Volatile organic compound profiling as a potential biomarker in irritable bowel syndrome: A feasibility study

K Van Malderen, N Hanning, H Lambrechts… - Frontiers in …, 2022 - frontiersin.org
Background: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder for which
no diagnostic tools are currently available. Patients are diagnosed using the Rome IV …

Reduced graphene oxide-metalloporphyrin sensors for human breath screening

BM Lee, A Eetemadi, I Tagkopoulos - Applied Sciences, 2021 - mdpi.com
The objective of this study is to validate reduced graphene oxide (RGO)-based volatile
organic compounds (VOC) sensors, assembled by simple and low-cost manufacturing, for …

Optimized sample preparation for fecal volatile organic compound analysis by gas chromatography–mass spectrometry

S el Manouni el Hassani, RJ Soers, DJC Berkhout… - Metabolomics, 2020 - Springer
Introduction Headspace gas chromatography–mass spectrometry (HS-GC–MS) is widely
considered the gold standard of quantitative fecal VOC analysis. However, guidelines …

Advances in celiac disease testing

T Pasinszki, M Krebsz - Advances in clinical chemistry, 2019 - Elsevier
Celiac disease (CD) is a T cell-mediated inflammatory autoimmune disorder of the upper
small intestine caused by the ingestion of gluten. It is increasingly recognized as a global …

Rethinking EBAD: Evolution of smart noninvasive detection of diabetes

S Afreen, JJ Zhu - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
A noninvasive detection technique of diabetes via monitoring the concentration of acetone in
exhaled breath (EB) has been approaching to groundbreaking innovations in the very recent …

[HTML][HTML] Detecting Clostridioides (Clostridium) difficile using canine teams: What does the nose know?

MK Charles, Y Wang, T Zurberg, J Kinna… - Infection Prevention in …, 2019 - Elsevier
Background Trained canines are capable of detecting Clostridioides (Clostridium) difficile
(CD) in the environment; however, the primary odour of interest on which the dogs alert is …

A bio-fluorometric acetone gas imaging system for the dynamic analysis of lipid metabolism in human breath

T Arakawa, N Mizukoshi, K Iitani, K Toma… - Chemosensors, 2021 - mdpi.com
We constructed an imaging system to measure the concentration of acetone gas by acetone
reduction using secondary alcohol dehydrogenase (S-ADH). Reduced nicotinamide …