[HTML][HTML] Contribution of the KSHV and EBV lytic cycles to tumourigenesis

O Manners, JC Murphy, A Coleman, DJ Hughes… - Current opinion in …, 2018 - Elsevier
Kaposi's Sarcoma-associated herpesvirus (KSHV) and Epstein Barr virus (EBV) are the
causative agents of several malignancies. Like all herpesviruses, KSHV and EBV undergo …

Kaposi's sarcoma and other manifestations of human herpesvirus 8

P Geraminejad, O Memar, I Aronson, PL Rady… - Journal of the American …, 2002 - Elsevier
Kaposi's sarcoma (KS) was described by Moritz Kaposi in 1872 and was known for an entire
century as a rare disorder of older men usually of Eastern European, Mediterranean, and/or …

Randomized phase II trial of matrix metalloproteinase inhibitor COL-3 in AIDS-related Kaposi's sarcoma: an AIDS Malignancy Consortium Study

BJ Dezube, SE Krown, JY Lee, KS Bauer… - Journal of clinical …, 2006 - ascopubs.org
Purpose Matrix metalloproteinases (MMPs) are involved in tumor metastasis and are
overexpressed in Kaposi's sarcoma (KS) cells. In a phase I trial of the MMP inhibitor COL-3 …

[HTML][HTML] Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich …

DP AuCoin, KS Colletti, SA Cei, I Papousková… - Virology, 2004 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8
(HHV8), has significant sequence homology to Epstein–Barr virus (EBV). In cell culture …

Wild-type Kaposi's sarcoma-associated herpesvirus isolated from the oropharynx of immune-competent individuals has tropism for cultured oral epithelial cells

KM Duus, V Lentchitsky, T Wagenaar, C Grose… - Journal of …, 2004 - Am Soc Microbiol
Based on the observation that wild-type Kaposi's sarcoma-associated herpesvirus (KSHV)
DNA can be detected in the oral cavity of healthy, immunocompetent individuals, we …

[PDF][PDF] Management of AIDS-related Kaposi sarcoma: advances in target discovery and treatment

BJ Dezube, L Pantanowitz… - AIDS READER-NEW …, 2004 - researchgate.net
Kaposi sarcoma (KS) is the most common tumor arising in HIV-infected patients and is
considered an AIDS-defining illness by CDC guidelines. Recent advances in the elucidation …

The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells

DA Haas, K Bala, G Büsche, M Weidner-Glunde… - PLoS …, 2013 - journals.plos.org
Kaposi's sarcoma (KS) is a mesenchymal tumour, which is caused by Kaposi's sarcoma
herpesvirus (KSHV) and develops under inflammatory conditions. KSHV-infected …

Degradation of TRIM32 is induced by RTA for Kaposi's sarcoma-associated herpesvirus lytic replication

Y Zhang, Z Dong, F Gu, Y Xu, Y Li, W Sun… - Journal of …, 2024 - Am Soc Microbiol
ABSTRACT TRIM32 is often aberrantly expressed in many types of cancers. Kaposi's
sarcoma-associated herpesvirus (KSHV) is linked with several human malignancies …

[HTML][HTML] The epidemiology of KSHV and its association with malignant disease

JN Martin - 2011 - europepmc.org
In, Moritz Kaposi, a Hungarian dermatologist, described six patients with multifocal brown–
red or blue–red nodules or plaques on the feet and hands (Kaposi, 1872). Initially called …

Diagnosis and epidemiology of human herpesvirus 8 infection

JN Martin - Seminars in hematology, 2003 - Elsevier
There is consensus that human herpesvirus 8 (HHV-8) is a necessary, albeit not sufficient,
causal agent of Kaposi's sarcoma (KS). In the past several years, there have been rapid …