Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy

M Hashemi, MS Moosavi, HM Abed, M Dehghani… - Pharmacological …, 2022 - Elsevier
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Oncofetal reprogramming in tumour development and progression

A Sharma, C Blériot, J Currenti, F Ginhoux - Nature Reviews Cancer, 2022 - nature.com
Embryonic development is characterized by rapidly dividing cells, cellular plasticity and a
highly vascular microenvironment. These features are similar to those of tumour tissue, in …

LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling

J Yang, F Liu, Y Wang, L Qu, A Lin - Cancer Letters, 2022 - Elsevier
Evidence accumulated over the past decade has verified that long non-coding RNAs
(lncRNAs) exert important functions in multiple cell programs. As a novel class of cellular …

Research progress on the circRNA/lncRNA-miRNA-mRNA axis in gastric cancer

X Zeng, J Xiao, X Bai, Y Liu, M Zhang, J Liu… - … -Research and Practice, 2022 - Elsevier
Gastric cancer is one of the most common malignant tumours worldwide. Genetic and
epigenetic alterations are key factors in gastric carcinogenesis and drug resistance to …

[HTML][HTML] Long non-coding RNAs: Biogenesis, functions, and clinical significance in gastric cancer

Y Liu, W Ding, W Yu, Y Zhang, X Ao, J Wang - Molecular Therapy …, 2021 - cell.com
Gastric cancer (GC) is one of the most prevalent malignant tumor types and the third leading
cause of cancer-related death worldwide. Its morbidity and mortality are very high due to a …

[HTML][HTML] Long Noncoding RNA H19: A Novel Therapeutic Target Emerging in Oncology Via Regulating Oncogenic Signaling Pathways

B Wu, Y Zhang, Y Yu, C Zhong, Q Lang… - Frontiers in Cell and …, 2021 - frontiersin.org
Long noncoding RNA H19 (H19) is an imprinting gene with only maternal expression that is
involved in regulating different processes in various types of cells. Previous studies have …

Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling

L Zhang, X Wang, E Nepovimova, Q Wu, W Wu… - Food and Chemical …, 2023 - Elsevier
Trichothecene mycotoxin deoxynivalenol (DON) negatively regulates immune response by
damaging host immune system and harming the organism's health. We hypothesized that …

Exploring the effect of Weifuchun capsule on the toll-like receptor pathway mediated HES6 and immune regulation against chronic atrophic gastritis

B Wang, W Zhou, H Zhang, W Wang, B Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Weifuchun capsule (WFC) is a traditional Chinese patent
medicine for chronic atrophic gastritis (CAG) in clinic. However, the mechanism of action of …

[HTML][HTML] A state-of-art of underlying molecular mechanisms and pharmacological interventions/nanotherapeutics for cisplatin resistance in gastric cancer

J Gupta, AT Ahmed, NA Tayyib, RS Zabibah… - Biomedicine & …, 2023 - Elsevier
The fourth common reason of death among patients is gastric cancer (GC) and it is a
dominant tumor type in Ease Asia. One of the problems in GC therapy is chemoresistance …

Fusobacterium nucleatum‐induced exosomal HOTTIP promotes gastric cancer progression through the microRNA‐885‐3p/EphB2 axis

Y Xin, X Li, M Zhang, Z Shang, Z Luo, Y Wang… - Cancer …, 2023 - Wiley Online Library
Recent studies have reported that Fusobacterium nucleatum (Fn) is associated with gastric
cancer (GC). Cancer‐derived exosomes contain key regulatory noncoding RNAs and are a …