Chronic Inflammation, Oxidative Stress and Metabolic Plasticity: Three Players Driving the Pro-Tumorigenic Microenvironment in Malignant Mesothelioma
I Fiorilla, S Martinotti, AM Todesco, G Bonsignore… - Cells, 2023 - mdpi.com
Malignant pleural mesothelioma (MPM) is a lethal and rare cancer, even if its incidence has
continuously increased all over the world. Asbestos exposure leads to the development of …
continuously increased all over the world. Asbestos exposure leads to the development of …
Malignant mesothelioma tumours: molecular pathogenesis, diagnosis, and therapies accompanying clinical studies
The pathetic malignant mesothelioma (MM) is a extremely uncommon and confrontational
tumor that evolves in the mesothelium layer of the pleural cavities (inner lining-visceral …
tumor that evolves in the mesothelium layer of the pleural cavities (inner lining-visceral …
Clonal gene signatures predict prognosis in mesothelioma and lung adenocarcinoma
Malignant pleural mesothelioma (MPM) is a rare but lethal pleural cancer with high
intratumor heterogeneity (ITH). A recent study in lung adenocarcinoma has developed a …
intratumor heterogeneity (ITH). A recent study in lung adenocarcinoma has developed a …
Prognostic value of EMT gene signature in malignant mesothelioma
L Wu, K Yoshihara, H Yun, S Karim, N Shokri… - International Journal of …, 2023 - mdpi.com
Malignant mesothelioma (MESO) consists of epithelioid, biphasic, and sarcomatoid
subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously …
subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously …
Mesothelioma malignancy and the microenvironment: molecular mechanisms
Simple Summary In the tumor microenvironment, interaction among tumor cells, immune
cells, stromal cells, and the extracellular matrix is vital to support pro-tumor mechanisms …
cells, stromal cells, and the extracellular matrix is vital to support pro-tumor mechanisms …
Enhancing Drug Delivery Efficacy Through Bilayer Coating of Zirconium-Based Metal–Organic Frameworks: Sustained Release and Improved Chemical Stability and …
The development of nanoparticle (NP)-based drug carriers has presented an exciting
opportunity to address challenges in oncology. Among the 100,000 available possibilities …
opportunity to address challenges in oncology. Among the 100,000 available possibilities …
[HTML][HTML] Global, regional, and national trends in mesothelioma burden from 1990 to 2019 and the predictions for the next two decades
W Zhu, J Liu, Y Li, Z Shi, S Wei - SSM-Population Health, 2023 - Elsevier
Objectives We aimed to analyze the secular trends in mesothelioma burden, the effect of
age, period, and birth cohort, and project the global burden over time. Material and methods …
age, period, and birth cohort, and project the global burden over time. Material and methods …
Molecular pathways in peritoneal mesothelioma: A minireview of new insights
Mesothelioma is a rare malignant neoplasm with poor survival. It mainly affects the pleura
(90%) but can arise in all serous cavities: peritoneum (5-10%), pericardium and tunica …
(90%) but can arise in all serous cavities: peritoneum (5-10%), pericardium and tunica …
Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library
Background Diffuse pleural mesothelioma (DPM) is an aggressive malignancy that, despite
recent treatment advances, has unacceptably poor outcomes. Therapeutic research in DPM …
recent treatment advances, has unacceptably poor outcomes. Therapeutic research in DPM …
Immunotherapy for mesothelioma: Moving beyond single immune check point inhibition
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm with low survival rates.
Platinum-based chemotherapy has represented the cornerstone of treatment for over a …
Platinum-based chemotherapy has represented the cornerstone of treatment for over a …