The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …

Oxidative stress plays an important role in the pathogenesis of chronic obstructive
pulmonary disease (COPD) caused by cigarette smoke and characterized by chronic …

Abstracts Background Studies have linked gaseous air pollutants to multiple health effects
via inflammatory pathways. Several major inflammatory biomarkers, including C-reactive …

Together with cities in higher-income nations, it is anticipated that the real global ozone is
rising in densely populated areas of Asia and Africa. This review aims to discuss the …

Our current understanding of the pathogenesis of skin aging includes the role of ultraviolet
light, visible light, infrared, pollution, cigarette smoke and other environmental exposures …

Despite recent advances in using biologicals that target Th2 pathways, glucocorticoids form
the mainstay of asthma treatment. Asthma morbidity and mortality remain high due to the …

Objective To study the regulatory relationship between ozone-induced mitophagy and
pyroptosis in lung epithelial cells. Results First, type I primary alveolar epithelial cells and …

Global warming has direct and indirect effects, as well as short-and long-term impacts on the
respiratory and skin barriers. Extreme temperature directly affects the airway epithelial …

Objective Chronic rhinosinusitis (CRS) is a highly prevalent and burdensome disease. The
pathophysiology is not fully elucidated, but environmental pollutants have been suggested …