Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led …

Alzheimer disease (AD) is a major cause of age-related dementia. We do not fully
understand AD aetiology and pathogenesis, but oxidative damage is a key component. The …

Increasing numbers of individuals suffer from neurodegenerative diseases, which are
characterized by progressive loss of neurons. Oxidative stress, in particular, the …

Reactive oxygen species (ROS) have been described to induce a broad range of redox-
dependent signaling reactions in physiological conditions. Nevertheless, an excessive …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

Alzheimer's disease (AD) is characterized by non-linear, genetic-driven pathophysiological
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …

Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …

Plant polyphenols are secondary metabolites characterized by one or more hydroxyl groups
binding to one or more aromatic rings [1]. Several thousand polyphenolic molecules have …

Inheritance of apolipoprotein E4 (APOE4) is a major risk factor for development of
Alzheimer's disease (AD). This lipoprotein, in contrast to apoE2, has arginine residues at …