One dimensional magneto-optical nanocomplex from silver nanoclusters and magnetite nanorods containing ordered mesocages for sensitive detection of PD-L1

X Huang, Z Zhang, J Chen, Z Mao, H Zhu, Y Liu… - Biosensors and …, 2021 - Elsevier
Programmed death ligand 1 (PD-L1) is a typical immune checkpoint protein, whose up-
regulation on the membrane of different tumor cells inhibits the immune response of T cells …

Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy

D Zheng, K Yang, Z Nie - View, 2021 - Wiley Online Library
Nanoparticle (NP)‐based vehicles are attractive for biomedical delivery and therapy, owing
to improved therapeutic efficiency and reduced adverse effects compared to free drugs …

The impact of antifouling layers in fabricating bioactive surfaces

Q Chen, D Zhang, J Gu, H Zhang, X Wu, C Cao… - Acta Biomaterialia, 2021 - Elsevier
Bioactive surfaces modified with functional peptides are critical for both fundamental
research and practical application of implant materials and tissue repair. However, when …

DNA Framework‐Based Topological Cell Sorters

F Yin, M Li, X Mao, F Li, X Xiang, Q Li… - Angewandte …, 2020 - Wiley Online Library
Molecular recognition in cell biological process is characterized with specific locks‐and‐
keys interactions between ligands and receptors, which are ubiquitously distributed on cell …

Recent advances in DNA-based molecular devices and their applications in cancer diagnosis

S Yang, R Zhu, S Wang, Y Xiong, G Zhou, Y Cao… - Coordination Chemistry …, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide and poses a great threat to human
health. In the past few years, diverse molecular devices have been constructed by using …

Network topology–directed design of molecular CPU for cell-like dynamic information processing

D Wang, Y Yang, F Chen, Y Lyu, W Tan - Science advances, 2022 - science.org
Natural cells (NCs) can automatically and continuously respond to fluctuant external
information and distinguish meaningful stimuli from weak noise depending on their powerful …

Aptamer-based liquid biopsy

L Wu, Y Wang, L Zhu, Y Liu, T Wang, D Liu… - ACS applied bio …, 2020 - ACS Publications
Liquid biopsy allows noninvasive and real-time analysis of tumor-derived circulating targets
in body fluids, holding great value for cancer diagnosis, prognosis, personalized therapy, as …

A Rapid SARS-CoV-2 nucleocapsid protein profiling assay with high sensitivity comparable to nucleic acid detection

J Liu, J Mao, M Hou, Z Hu, G Sun, S Zhang - Analytical Chemistry, 2022 - ACS Publications
Existing nucleic acid and antigen profiling methods for COVID-19 diagnosis fail to
simultaneously meet the demands in sensitivity and detection speed, hampering them from …

Extracellular ion-responsive logic sensors utilizing DNA dimeric nanoassemblies on cell surface and application to boosting AS1411 internalization

P Peng, Q Wang, Y Du, H Wang, L Shi, T Li - Analytical Chemistry, 2020 - ACS Publications
High levels of extracellular H+ and K+ are unique features of the tumor microenvironment
and have shown great promise for use in cancer-targeted drug delivery. Here, we design H+ …

Designer, programmable 3D DNA nanodevices to probe biological systems

A Rajwar, S Kharbanda… - ACS Applied Bio …, 2020 - ACS Publications
DNA nanotechnology is a unique field that provides simple yet robust design techniques for
self-assembling nanoarchitectures with extremely high potential for biomedical applications …