DNA Framework‐Enabled Three Dimensional Organization of Antiarrhythmic Drugs for Radiofrequency Catheter Ablation

H Chen, F Li, Y Ge, J Liu, X Xing, M Li, Z Ge… - Advanced …, 2024 - Wiley Online Library
Pre‐organizing molecular drug within a microenvironment is crucial for the development of
efficient and controllable therapeutic systems. Here, we report the use of tetrahedral DNA …

Advances in DNA walking nanomachine‐based biosensors

B Shen, L Li, M Guo, X Li, Y Fan, X Li… - Interdisciplinary …, 2024 - Wiley Online Library
The field of DNA nanotechnology has evolved beyond the realm of controllable movements
and randomly shaped nanostructures, now encompassing a diverse array of nanomachines …

A DNA tetrahedron dimer for dual membrane protein logic recognition and interaction inhibition

Y Zhang, M Lin, J Yao, X Xu - Chemical Communications, 2024 - pubs.rsc.org
Here, we report a DNA tetrahedron dimer for dual membrane protein logic recognition and
interaction inhibition. The DNA tetrahedron dimer not only detects dual proteins that are both …

Stable DNA Aptamer–Metal–Organic Framework as Horseradish Peroxidase Mimic for Ultra-Sensitive Detection of Carcinoembryonic Antigen in Serum

L Sha, M Zhu, F Lin, X Yu, L Dong, L Wu, R Ding, S Wu… - Gels, 2021 - mdpi.com
Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. For CEA
detection, a novel type of metal–organic framework (MOF) was prepared by grafting CEA …

[HTML][HTML] Acidic microenvironment triggered in situ assembly of activatable three-arm aptamer nanoclaw for contrast-enhanced imaging and tumor growth inhibition in …

J Huang, Y Wu, H He, W Ma, J Liu, H Cheng, H Sun… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Static assembled multivalent DNA nanotheranostics system have encountered
some bottleneck problems in cancer imaging and therapy, such as poor penetration and …

Multiplex lateral flow test strip for detection of carbapenemase genes using barcoded tetrahedral DNA capture probe-based biosensing interface

Y Xu, J Luo, W Lai, J Da, B Yang, X Luo, L Zhan, Y Fei… - Microchimica Acta, 2023 - Springer
Carbapenem-resistant Enterobacterales pose significant global health challenges due to
their rapid spread and ability to hydrolyse various beta-lactam antibiotics. Rapid tests for …

Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles

Y Ren, K Ge, W Lu, X Xie, Y Lu, M Wang… - ACS Applied Materials …, 2023 - ACS Publications
Tumor-derived extracellular vesicles (T-EVs) hold great promise for understanding cancer
biology and improving cancer diagnostics and therapeutics. Herein, we developed …

Dually stimulative single-chain polymeric nano lock with dynamic ligands for sensitive detection of circulating tumor cells

M Cui, X Chen, X Luo, Z Zhou, Z Chen, Z Zhou… - Biosensors and …, 2022 - Elsevier
Circulating tumor cells (CTCs) are important markers for cancer diagnosis and monitoring.
However, CTCs detection remains challenging due to their scarcity, where most of the …

Recent advances in the applications of DNA frameworks in liquid biopsy: A review

X Duan, W Qin, J Hao, X Yu - Analytica Chimica Acta, 2024 - Elsevier
Cancer is one of the serious threats to public life and health. Early diagnosis, real-time
monitoring, and individualized treatment are the keys to improve the survival rate and …

Development of an Electrochemical Microfluidic System with a Nanoscale Deoxyribonucleic Acid Framework for Detection of Circulating Tumor Cells

Y Xu, C Wang, N Wu, X Mi - ACS Applied Nano Materials, 2024 - ACS Publications
Circulating tumor cells (CTCs) are cells that have detached from primary tumors and entered
into peripheral blood; they are often associated with cancer metastasis. Accurate and …