DNA vaccines have inherent advantages compared to other vaccine types, including safety,
rapid design and construction, ease and speed to manufacture, and thermostability …

Dengue viruses 1-4 (DENV 1-4) and Zika virus (ZIKV) are closely related flaviviruses
transmitted by Aedes mosquitoes that co-circulate in Asia, the Americas, Africa, and …

Abstract Dengue viruses (DENV1–4) are the most prevalent arboviruses in humans and a
major public health concern. Understanding immune mechanisms that modulate DENV …

Dengue virus serotypes 1 to 4 (DENV1–4) and Zika virus (ZIKV) are mosquito-borne
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …

Zika virus (ZIKV), an arbovirus transmitted by mosquitoes, was identified as a cause of
congenital disease during a major outbreak in the Americas in 2016. Vaccine design …

Sequential dengue virus (DENV) infections often generate neutralizing antibodies against
all four DENV serotypes and sometimes, Zika virus. Characterizing cross-flavivirus broadly …

Passive immunization with polyclonal hyper immunoglobulin (HIG) therapy represents a
proven strategy by transferring immunoglobulins to patients to confer immediate protection …

Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-
reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or …

Flaviviruses are a genus within the Flaviviridae family of positive-strand RNA viruses and
are transmitted principally through mosquito and tick vectors. These viruses are responsible …

Zika virus (ZKV) infection in a pregnant woman, especially during the first trimester, often
results in congenital anomalies. However, the pathogenic mechanism is unknown and one …