Advances in oral immunomodulating therapies in relapsing multiple sclerosis

T Derfuss, M Mehling, A Papadopoulou… - The Lancet …, 2020 - thelancet.com
Background Oral treatment options for disease-modifying therapy in relapsing multiple
sclerosis have substantially increased over the past decade with four approved oral …

[HTML][HTML] Progress in the Application of Drugs for the Treatment of Multiple Sclerosis

W Wei, D Ma, L Li, L Zhang - Frontiers in Pharmacology, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune and chronic inflammatory demyelinating disease
of the central nervous system (CNS), which gives rise to focal lesion in CNS and cause …

Treatment escalation vs immediate initiation of highly effective treatment for patients with relapsing-remitting multiple sclerosis: data from 2 different national strategies

T Spelman, M Magyari, F Piehl, A Svenningsson… - JAMA …, 2021 - jamanetwork.com
Importance Treatment strategies for relapsing-remitting multiple sclerosis (RRMS) vary
markedly between Denmark and Sweden. The difference in the association of these national …

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis

T Kalincik, EK Havrdova, D Horakova… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective Oral immunotherapies have become a standard treatment in relapsing-remitting
multiple sclerosis. Direct comparison of their effect on relapse and disability is needed …

[HTML][HTML] Efficacy and safety outcomes with diroximel fumarate after switching from prior therapies or continuing on DRF: results from the phase 3 EVOLVE-MS-1 study

S Wray, F Then Bergh, A Wundes, DL Arnold… - Advances in …, 2022 - Springer
Introduction Diroximel fumarate (DRF) is an oral fumarate for relapsing multiple sclerosis
(MS) with the same active metabolite as dimethyl fumarate (DMF). DRF has a safety/efficacy …

[HTML][HTML] Comparative effectiveness of delayed-release dimethyl fumarate versus interferon, glatiramer acetate, teriflunomide, or fingolimod: results from the German …

S Braune, S Grimm, P van Hövell, U Freudensprung… - Journal of …, 2018 - Springer
Background Comparative effectiveness (CE) research allows real-world treatment
comparisons using outcome measurements important to physicians/patients. This German …

Relapses and disease-modifying drug treatment in pregnancy and live birth in US women with MS

MK Houtchens, NC Edwards, AL Phillips - Neurology, 2018 - AAN Enterprises
Objective To evaluate relapse rates and disease-modifying drug (DMD) treatment in US
women with multiple sclerosis (MS) and a live birth. Methods This retrospective …

[HTML][HTML] Comparative effectiveness of dimethyl fumarate versus fingolimod and teriflunomide among MS patients switching from first-generation platform therapies in …

D Ontaneda, J Nicholas, M Carraro, J Zhou… - Multiple sclerosis and …, 2019 - Elsevier
Background Previous real-world comparative research of MS disease modifying therapies
(DMTs) in the overall population has suggested dimethyl fumarate (DMF) to be comparable …

Comparative effectiveness of teriflunomide and dimethyl fumarate: a nationwide cohort study

MD Buron, TA Chalmer, F Sellebjerg, J Frederiksen… - Neurology, 2019 - AAN Enterprises
Objective To compare on-treatment efficacy and discontinuation outcomes in teriflunomide
(TFL) and dimethyl fumarate (DMF) in the treatment of relapsing-remitting multiple sclerosis …

Comparative effectiveness of teriflunomide vs dimethyl fumarate in multiple sclerosis

DA Laplaud, R Casey, L Barbin, M Debouverie… - Neurology, 2019 - AAN Enterprises
Objective In this study, we compared the effectiveness of teriflunomide (TRF) and dimethyl
fumarate (DMF) on both clinical and MRI outcomes in patients followed prospectively in the …