Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in
response to various intrinsic and extrinsic stimuli, as well as developmental signals …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

Background Studying epigenetics is expected to provide precious information on how
environmental factors contribute to type 2 diabetes mellitus (T2DM) at the genomic level …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

Non-coding RNAs (ncRNAs) are a class of functional RNAs that regulate gene expression in
a post-transcriptional manner. NcRNAs include microRNAs, long non-coding RNAs and …

Nucleic acid-based therapeutics are currently developed at large scale for prevention and
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …

Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …

Periodontal ligament stem cells (PDLSCs) are mesenchymal stem cells derived from dental
tissues with multidirectional differentiation potential and excellent self-renewing ability …

Alzheimer's disease (AD) results in progressive cognitive decline owing to the accumulation
of amyloid plaques and hyperphosphorylated tau. MicroRNAs (miRNAs) have attracted …

Senescence of adipose precursor cells (APC) impairs adipogenesis, contributes to the age‐
related subcutaneous adipose tissue (SAT) dysfunction, and increases risk of type 2 …