Dysregulation of long non-coding RNA profile in peripheral blood of multiple sclerosis patients

R Dastmalchi, S Ghafouri-Fard, MD Omrani… - Multiple sclerosis and …, 2018 - Elsevier
Multiple sclerosis (MS) is a chronic autoimmune disorder in which dysregulation or aberrant
expressions of several immune-related genes have been noted. More recently, the …

Transcriptomic and open chromatin atlas of high-resolution anatomical regions in the rhesus macaque brain

S Yin, K Lu, T Tan, J Tang, J Wei, X Liu, X Hu… - Nature …, 2020 - nature.com
The rhesus macaque is a prime model animal in neuroscience. A comprehensive
transcriptomic and open chromatin atlas of the rhesus macaque brain is key to a deeper …

LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1

X Yu, MS Song, PZ Rong, XJ Chen… - Journal of cellular …, 2022 - Wiley Online Library
Recent evidence indicates that the abnormal differentiation of bone marrow‐derived
mesenchymal stem cells (BMSCs) plays a pivotal role in the pathogenesis of osteoporosis …

Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation

I Salvato, L Ricciardi, J Dal Col, A Nigro… - Frontiers in …, 2023 - frontiersin.org
Introduction The RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to
posttranscriptional regulation of genes involved in inflammation and cellular senescence …

Cross-talk between mitochondrial dysfunction-provoked oxidative stress and aberrant noncoding RNA expression in the pathogenesis and pathophysiology of SLE

CY Tsai, SC Hsieh, CS Lu, TH Wu, HT Liao… - International Journal of …, 2019 - mdpi.com
Systemic lupus erythematosus (SLE) is a prototype of systemic autoimmune disease
involving almost every organ. Polygenic predisposition and complicated epigenetic …

[HTML][HTML] Non-Coding RNAs in glioma microenvironment and angiogenesis

D Li, Z Zhang, C Xia, C Niu, W Zhou - Frontiers in Molecular …, 2021 - frontiersin.org
Glioma, especially glioblastoma, is the most common and lethal brain tumor. In line with the
complicated vascularization processes and the strong intratumoral heterogeneity, tumor …

circDlgap4 alleviates cerebral ischaemic injury by binding to AUF1 to suppress oxidative stress and neuroinflammation

H Liu, W Zheng, Z Song - Molecular Neurobiology, 2022 - Springer
Ischaemic stroke is one of the most common causes of mortality and morbidity. circDlgap4
has been implicated in ischemia/reperfusion injury through an unknown mechanism. Here …

Changes and relationship of N6-methyladenosine modification and long non-coding RNAs in oxidative damage induced by cadmium in pancreatic β-cells

T Qu, Y Mou, J Dai, X Zhang, M Li, S Gu, Z He - Toxicology Letters, 2021 - Elsevier
Abstract N 6-methyladenosine (m 6 A) modification and m 6 A-modified Long non-coding
RNAs (LncRNAs) play crucial roles in various pathological processes, yet their changes and …

Loss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype

S Ryu, M Jung, C Kim, H Kang, S Han, S Cha… - Cell Death & …, 2022 - nature.com
HuD, an RNA binding protein, plays a role in the regulation of gene expression in certain
types of cells, including neuronal cells and pancreatic β-cells, via RNA metabolism. Its …

Mechanisms of antisense transcription initiation with implications in gene expression, genomic integrity and disease pathogenesis

P Barman, D Reddy, SR Bhaumik - Non-coding RNA, 2019 - mdpi.com
Non-coding antisense transcripts arise from the strand opposite the sense strand. Over 70%
of the human genome generates non-coding antisense transcripts while less than 2% of the …