[HTML][HTML] Deficiency of the RNA-binding protein ELAVL1/HuR leads to the failure of endogenous and exogenous neuroprotection of retinal ganglion cells

A Pacwa, J Machowicz, S Akhtar, P Rodak… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction ELAVL1/HuR is a keystone regulator of gene expression at the
posttranscriptional level, including stress response and homeostasis maintenance. The aim …

Adaptor proteins in long noncoding RNA biology

E Dangelmaier, A Lal - Biochimica et Biophysica Acta (BBA)-Gene …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) are a heterogeneous class of noncoding RNAs that have
gained increasing attention due to their vital roles in the regulation of diverse cellular …

Increased MALAT1 expression contributes to cisplatin resistance in non‑small cell lung cancer

Y Cui, G Li, X Zhang, F Dai… - Oncology Letters, 2018 - spandidos-publications.com
Cisplatin‑based chemotherapy is commonly used for the clinical treatment of patients with
non‑small cell lung cancer (NSCLC). However, the anti‑tumor efficacy of cisplatin is limited …

Protective Effect of Quercetin against H2O2‐Induced Oxidative Damage in PC‐12 Cells: Comprehensive Analysis of a lncRNA‐Associated ceRNA Network

Z Zhang, P Yi, M Yi, X Tong, X Cheng… - Oxidative Medicine …, 2020 - Wiley Online Library
Quercetin is a bioflavonoid with potential antioxidant properties. However, the mechanisms
underlying its effects remain unclear. Herein, we focused on integrating long noncoding …

Comprehensive survey and comparative assessment of RNA-binding residue predictions with analysis by RNA type

K Wang, G Hu, Z Wu, H Su, J Yang… - International journal of …, 2020 - mdpi.com
With close to 30 sequence-based predictors of RNA-binding residues (RBRs), this
comparative survey aims to help with understanding and selection of the appropriate tools …

The western diet regulates hippocampal microvascular gene expression: an integrated genomic analyses in female mice

S Nuthikattu, D Milenkovic, J Rutledge… - Scientific Reports, 2019 - nature.com
Hyperlipidemia is a risk factor for dementia, and chronic consumption of a Western Diet
(WD) is associated with cognitive impairment. However, the molecular mechanisms …

Discovery of Salidroside as a Novel Non-Coding RNA Modulator to Delay Cellular Senescence and Promote BK-Dependent Apoptosis in Cerebrovascular Smooth …

Y Ge, B Zhang, J Song, Q Cao, Y Bu, P Li, Y Bai… - International Journal of …, 2023 - mdpi.com
Cardiovascular aging has been reported to accelerate in spaceflights, which is a great
potential risk to astronauts' health and performance. However, current exercise routines are …

[HTML][HTML] LncRNAs and circular RNAs as endothelial cell messengers in hypertension: mechanism insights and therapeutic potential

JR Zhang, HJ Sun - Molecular Biology Reports, 2020 - Springer
Endothelial cells are major constituents in the vasculature, and they act as important players
in vascular homeostasis via secretion/release of vasodilators and vasoconstrictors. In …

Long non-coding RNAs, novel offenders or guardians in multiple sclerosis: A scoping review

A Jalaiei, MR Asadi, H Sabaie, H Dehghani… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous
system, is one of the most common neurodegenerative diseases worldwide. MS results in …

LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer

X Si, G Zhang, M Li, M Yao, X Shi, Z Dong, S Gao - Pharmacology, 2023 - karger.com
Introduction: During breast cancer chemotherapy, the chemoresistance that frequently
accompanies the treatment has become a big challenge. Long noncoding RNAs (LncRNAs) …