Host genetic variations play a significant role in conferring predisposition to infection. In this
study, we examined the immune mechanisms underlying the host genetic predisposition to …

Although its efficiency against all Schistosoma species, praziquantel (PZQ) shows low
efficacy against schistosomula and juvenile stages. The potential for development of …

Schistosomiasis is second only to malaria as the most devastating parasitic disease in the
world. It is caused by the helminths Schistosoma mansoni (S. mansoni), S. haematobium, or …

Schistosomes are the cause of the most significant helminth disease of humans. Their
unusual sexual biology is intriguing. Instead of being hermaphroditic, as is the rule in other …

Schistosomiasis and malnutrition are often overlapped in poor communities, resulting in
disproportionately high mortality rates. Currently, fragmented data make it difficult to define …

Background The role of pathogen genotype in determining disease severity and
immunopathology has been studied intensively in microbial pathogens including bacteria …

Pomphorhynchus laevis, a fish acanthocephalan parasite, manipulates the behaviour of its
gammarid intermediate host to increase its trophic transmission to the definitive host …

Schistosome–host interaction is influenced by multiple factors, such as the type of immune
response developed by the host, host genetic background, intensity, and number of …

Experiments were carried out to analyze the biological characteristics of two sympatric
isolates of Schistosoma mansoni derived from humans and murines in a low endemic …

Although the current treatment of schistosomiasis relies largely on praziquantel (PZQ), it has
not significantly reduced the overall number of disease cases, perhaps due to inevitable …