Bioinformatic approaches for studying the microbiome of fermented food
LH Walsh, M Coakley, AM Walsh… - Critical Reviews in …, 2023 - Taylor & Francis
High-throughput DNA sequencing-based approaches continue to revolutionise our
understanding of microbial ecosystems, including those associated with fermented foods …
understanding of microbial ecosystems, including those associated with fermented foods …
[HTML][HTML] Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans
A mysterious feature of Crohn's disease (CD) is the extra-intestinal manifestation of"
creeping fat"(CrF), defined as expansion of mesenteric adipose tissue around the inflamed …
creeping fat"(CrF), defined as expansion of mesenteric adipose tissue around the inflamed …
[HTML][HTML] No evidence for a common blood microbiome based on a population study of 9,770 healthy humans
CCS Tan, KKK Ko, H Chen, J Liu, M Loh… - Nature …, 2023 - nature.com
Human blood is conventionally considered sterile but recent studies suggest the presence of
a blood microbiome in healthy individuals. Here we characterized the DNA signatures of …
a blood microbiome in healthy individuals. Here we characterized the DNA signatures of …
Effects of 'healthy'fecal microbiota transplantation against the deterioration of depression in fawn-hooded rats
Depression is a recurrent, heterogeneous mood disorder occurring in more than 260 million
people worldwide. Gut microbiome dysbiosis is associated with the development of …
people worldwide. Gut microbiome dysbiosis is associated with the development of …
Gut microbiome composition is predictive of incident type 2 diabetes in a population cohort of 5,572 Finnish adults
OBJECTIVE To examine the previously unknown long-term association between gut
microbiome composition and incident type 2 diabetes in a representative population cohort …
microbiome composition and incident type 2 diabetes in a representative population cohort …
Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome
AL Edwinson, L Yang, S Peters, N Hanning… - Nature …, 2022 - nature.com
Intestinal proteases mediate digestion and immune signalling, while increased gut
proteolytic activity disrupts the intestinal barrier and generates visceral hypersensitivity …
proteolytic activity disrupts the intestinal barrier and generates visceral hypersensitivity …
Phylogeny-aware analysis of metagenome community ecology based on matched reference genomes while bypassing taxonomy
We introduce the operational genomic unit (OGU) method, a metagenome analysis strategy
that directly exploits sequence alignment hits to individual reference genomes as the …
that directly exploits sequence alignment hits to individual reference genomes as the …
Menopause is associated with an altered gut microbiome and estrobolome, with implications for adverse cardiometabolic risk in the hispanic community health study …
Menopause is a pivotal period during which loss of ovarian hormones increases
cardiometabolic risk and may also influence the gut microbiome. However, the menopause …
cardiometabolic risk and may also influence the gut microbiome. However, the menopause …
Links between gut microbiome composition and fatty liver disease in a large population sample
MO Ruuskanen, F Åberg, V Männistö, AS Havulinna… - Gut …, 2021 - Taylor & Francis
Fatty liver disease is the most common liver disease in the world. Its connection with the gut
microbiome has been known for at least 80 y, but this association remains mostly unstudied …
microbiome has been known for at least 80 y, but this association remains mostly unstudied …
[HTML][HTML] Robustness of cancer microbiome signals over a broad range of methodological variation
In 2020, we identified cancer-specific microbial signals in The Cancer Genome Atlas
(TCGA). Multiple peer-reviewed papers independently verified or extended our findings …
(TCGA). Multiple peer-reviewed papers independently verified or extended our findings …