Inflammation: the driver of poor outcomes among children with severe acute malnutrition?
Severe acute malnutrition (SAM) is the most life-threatening form of undernutrition and
underlies at least 10% of all deaths among children younger than 5 years in low-income …
underlies at least 10% of all deaths among children younger than 5 years in low-income …
Pathologic inflammation in malnutrition is driven by proinflammatory intestinal microbiota, large intestine barrier dysfunction, and translocation of bacterial …
Acute malnutrition, or wasting, is implicated in over half of all deaths in children under five
and increases risk of infectious disease. Studies in humans and preclinical models have …
and increases risk of infectious disease. Studies in humans and preclinical models have …
The correlation between dysfunctional intestinal flora and pathology feature of patients with pulmonary tuberculosis
S Ye, L Wang, S Li, Q Ding, Y Wang, X Wan… - Frontiers in Cellular …, 2022 - frontiersin.org
Introduction Recent studies have provided insights into the important contribution of gut
microbiota in the development of Pulmonary Tuberculosis (PTB). As a chronic consumptive …
microbiota in the development of Pulmonary Tuberculosis (PTB). As a chronic consumptive …
Inflammatory profiles in febrile children with moderate and severe malnutrition presenting at-hospital in Uganda are associated with increased mortality
AM Weckman, CR McDonald, M Ngai… - …, 2023 - thelancet.com
Summary Background Children in Africa carry a disproportionate burden of malnutrition and
infectious disease. Together, malnutrition and infection are major contributors to global child …
infectious disease. Together, malnutrition and infection are major contributors to global child …
Inflammatory stimuli alter bone marrow composition and compromise bone health in the malnourished host
EY Osorio, Z Gugala, GT Patterson, G Palacios… - Frontiers in …, 2022 - frontiersin.org
Inflammation has a role in the pathogenesis of childhood malnutrition. We investigated the
effect of malnutrition and inflammatory challenge on bone marrow composition and bone …
effect of malnutrition and inflammatory challenge on bone marrow composition and bone …
Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells
TN Phiri, K Mutasa, S Rukobo, M Govha… - Science …, 2023 - science.org
Children with severe acute malnutrition (SAM) have high infectious mortality and morbidity,
implicating defects in their immune defenses. We hypothesized that circulating innate …
implicating defects in their immune defenses. We hypothesized that circulating innate …
The synergistic interaction of systemic inflammation, dysbiosis and antimicrobial resistance promotes growth restriction in children with acute severe malnutrition: An …
R Arredondo-Hernandez, C Siebe… - Frontiers in …, 2022 - frontiersin.org
A healthy development is denied to millions of children worldwide as harsh life conditions
manifest themselves in an altered inflammation-prone microbiome crosstalk environment …
manifest themselves in an altered inflammation-prone microbiome crosstalk environment …
A murine model of maternal micronutrient deficiencies and gut inflammatory host-microbe interactions in the offspring
Background & Aims Micronutrient deficiency (MND)(ie, lack of vitamins and minerals) during
pregnancy is a major public health concern. Historically, studies have considered …
pregnancy is a major public health concern. Historically, studies have considered …
[HTML][HTML] Choline, DHA, and Diarrheal Disease Associated with Growth Faltering in a Case-Control Study
JN Diaz, SJL Dulience, N Wolthausen, X Jiang… - Current Developments …, 2022 - Elsevier
Background Children with recurrent infectious diarrhea are susceptible to growth faltering.
DHA and choline may play a role in this relationship due to their involvement in lipid …
DHA and choline may play a role in this relationship due to their involvement in lipid …
Association between severe acute malnutrition in childhood and hematological disorders in adulthood: the Lwiro follow-up study in the Eastern Democratic Republic …
A Bedha, T Shindano, MP Hermans, V Havelange… - BMC nutrition, 2023 - Springer
Background Despite growing evidence on the short-term deleterious effects of severe acute
malnutrition (SAM) in childhood on hematopoiesis, little is known about the long-term …
malnutrition (SAM) in childhood on hematopoiesis, little is known about the long-term …