Bullous pemphygoid and novel therapeutic approaches

GM D'Agostino, G Rizzetto, A Marani, S Marasca… - Biomedicines, 2022 - mdpi.com
Bullous pemphigoid is a subepidermal blistering disease associated with autoantibodies
(auto-ab) to BP180 and BP230 which affects elderly patients, predominately. Although it is a …

Omalizumab as an adjuvant in food allergen immunotherapy

JA Dantzer, RA Wood - Current opinion in allergy and clinical …, 2021 - journals.lww.com
The use of anti-IgE antibody as an adjunct to food allergen OIT has been an expanding area
of research with several additional trials underway. Significant progress has been made in …

[HTML][HTML] Pediatric usage of omalizumab: a promising one

L Yu, H Zhang, J Pan, L Ye - World Allergy Organization Journal, 2021 - Elsevier
Allergic and related diseases have a substantial epidemiological impact on the pediatric
population. Small molecule-based medicines have been traditionally used to manage the …

Advancements in bullous pemphigoid treatment: a comprehensive pipeline update

M Karakioulaki, K Eyerich, A Patsatsi - American Journal of Clinical …, 2024 - Springer
Bullous pemphigoid (BP) is a common autoimmune bullous disease affecting mainly the
elderly, with rising incidence due to increased life expectancy. This disease is characterized …

Impact of probiotic bacteria on respiratory allergy disorders

D Jakubczyk, S Górska - Frontiers in Microbiology, 2021 - frontiersin.org
Respiratory allergy is a common disease with an increased prevalence worldwide. The
effective remedy is still unknown, and a new therapeutic approach is highly desirable. The …

Monoclonal antibodies targeting small airways: a new perspective for biological therapies in severe asthma

C Lombardi, M Cottini, A Berti, P Comberiati - Asthma Research and …, 2022 - Springer
Small airway dysfunction (SAD) in asthma is characterized by the inflammation and
narrowing of airways with less of 2 mm in diameter between generations 8 and 23 of the …

IFN‐γ/IL‐6 and related cytokines in chronic spontaneous urticaria: evaluation of their pathogenetic role and changes during omalizumab therapy

T Grieco, A Porzia, G Paolino, C Chello… - International Journal …, 2020 - Wiley Online Library
Background Recent studies highlight that high levels of cytokines may precede the onset of
many systemic autoimmune disorders and may also be related to chronic spontaneous …

Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy

K Mengrelis, G Niederacher, L Prickler, V Kainz… - Cells, 2024 - mdpi.com
Up to a third of the world's population suffers from allergies, yet the effectiveness of available
preventative measures remains, at large, poor. Consequently, the development of …

Novel Lung Growth Strategy with Biological Therapy Targeting Airway Remodeling in Childhood Bronchial Asthma

M Tsuge, M Ikeda, H Tsukahara - Children, 2022 - mdpi.com
Anti-inflammatory therapy, centered on inhaled steroids, suppresses airway inflammation in
asthma, reduces asthma mortality and hospitalization rates, and achieves clinical remission …

The expression and function of CD300 molecules in the main players of allergic responses: mast cells, basophils and eosinophils

J Vitallé, I Terrén, A Orrantia, A Bilbao… - International journal of …, 2020 - mdpi.com
Allergy is the host immune response against non-infectious substances called allergens.
The prevalence of allergic diseases is increasing worldwide. However, while some drugs …